Jan Hartmann, M.D.
@janhartmannmd.bsky.social
Bringing Med to MedTech - Physician, Scientist, Photographer, Traveler, Berliner, Immigrant đ©đȘđșđž - Views=My own, Like/RTâ Endorsement; Haemonetics employee
Contemporary Operator Procedural Volumes and Outcomes for TAVR and MTEER in the US url: jamanetwork.com/journals/jam...
Contemporary Operator Procedural Volumes and Outcomes for TAVR and MTEER in the US
This cohort study determines whether an operator-level association of volume and outcomes exists for transcatheter aortic valve replacement (TAVR) and mitral transcatheter edge-to-edge repair (MTEER) ...
jamanetwork.com
Age-Adjusted D-Dimer Cutoff in Suspected Deep Vein Thrombosis url: jamanetwork.com/journals/jam...
Age-Adjusted D-Dimer Cutoff in Suspected Deep Vein Thrombosis
This prospective management outcome study conducted at multiple centers in Belgium, Canada, France, and Switzerland assesses whether using an age-adjusted D-dimer cutoff allows clinicians to safely ru...
jamanetwork.com
Our article on the trial of the HN cartridge for the TEGÂź 6s system featured in current issue of @anesthesiology.bsky.social. A big thank you to our team of coâauthors, local PIs and their teams, and all the participating patients who made this possible. www.linkedin.com/posts/anesth...
#anesthesiology #anesthesiologist #anesthesia #medicalresearch | Anesthesiology Journals
A heparinase-containing cartridge for the TEGÂź 6s system to neutralize this effect was recently cleared by the U.S. Food and Drug Administration, but validation in clinical settings had been limited. ...
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#teg6s #cardiacsurgery #patientbloodmanagement #hemostasis #medicalresearch | Haemonetics
A multicenter study highlighted in Anesthesiology Journals clinically validated our TEGÂź 6s Global Hemostasis â HN cartridge by demonstrating high correlation with established assays in heparinized pa...
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Liberal or Restrictive Postoperative Transfusion in Cardiac Risk jamanetwork.com/journals/jam...
Liberal or Restrictive Postoperative Transfusion in Cardiac Risk
This randomized clinical trial tests whether a liberal compared with a restrictive transfusion strategy lowers the risk of a cardiac event 90 days after major vascular or general surgery among patient...
jamanetwork.com
Preparing the Civilian Health Care System for Wartime url: jamanetwork.com/journals/jam...
Preparing the Civilian Health Care System for Wartime
This Viewpoint discusses the need for the US health care system to prepare for war casualties through military and civilian health care collaboration.
jamanetwork.com
Monoclonal gammopathy of undetermined significance is a common, asymptomatic plasma-cell disorder in older adults that can progress to cancer or systemic illness. Diagnosis warrants follow-up, but treatment is not required unless progression is confirmed. Learn more: nej.md/473uOsj
âFor physicianâscientists conducting early clinical trials, the results could best be described as miraculous.â đ§Ș 2025 #LaskerAward winners M. Welsh, J. GonzĂĄlez, & P. Negulescu developed life-saving #cysticfibrosis treatments. @nejm.org #Lasker2025
Transformative Research in Cystic Fibrosis | NEJM
Michael Welsh, JesĂșs GonzĂĄlez, and Paul Negulescu have won the 2025 LaskerâDeBakey Clinical Medical Research Award for their roles in developing treatments for cystic fibrosis.
nejm.org
âThe insights of Görlich, McKnight, and their colleagues are being harnessed in medical research.â đ§Ș Read how low-complexity domains of proteins impact human health in @nejm.org #LaskerAward #Lasker2025 @mpi-nat.bsky.social #phaseseparation #biophysics www.nejm.org/doi/full/10....
Surprisingly Complex Assemblies from Low-Complexity Domains | NEJM
Drs. Görlich and McKnight have won the 2025 Albert Lasker Award for Basic Medical Research for showing that low-complexity domains of proteins lack structure on their own and yet can form assembled .....
nejm.org
"Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants" ascpt.onlinelibrary.wiley.com/doi/abs/10.1...
Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in ClopidogrelâTreated Participants
Black individuals undergoing percutaneous coronary intervention (PCI) experience higher rates of major adverse cardiovascular events (MACE) than non-Black individuals. This study assessed the racial ...
ascpt.onlinelibrary.wiley.com
"Long-Term Outcomes of the DanGer Shock Trial" www.nejm.org/doi/full/10....
Long-Term Outcomes of the DanGer Shock Trial | NEJM
In patients with STEMI with cardiogenic shock, early mechanical support with a microaxial pump reduced the risk of death at 180 days, with the survival benefit persisting up to 10 years despite dev...
nejm.org
"Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation" jamanetwork.com/journals/jam...
Discontinuation of Anticoagulant Therapy After Catheter Ablation for Atrial Fibrillation
This randomized clinical trial compares discontinuing vs continuing oral anticoagulant therapy in patients without documented atrial arrhythmia recurrence after catheter ablation for atrial fibrillati...
jamanetwork.com
"Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis" www.thelancet.com/journals/lan...
Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis
These findings add to the evidence that clopidogrel monotherapy is superior to aspirin monotherapy for MACCE prevention with no increase in the risk of bleeding, and support the preferential use of cl...
thelancet.com
In patients with heparin-induced thrombocytopenia, pathogenic antibodies were found to be monoclonal, which challenges previous views of HIT as a polyclonal disorder and suggests new avenues for diagnosis and treatment. Full study results: nej.md/4pkaYAq #MedSky #CardioSky
Rainbow over Sandy Bay â Rockport, MA đ
Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis url: academic.oup.com/eurheartj/ar...
Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis
AbstractBackground and Aims. Dual antiplatelet therapy (DAPT) de-escalation strategies improve outcomes after percutaneous coronary intervention (PCI) comp
academic.oup.com
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery | New England Journal of Medicine www.nejm.org/doi/full/10....
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery | NEJM
Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic hemodilu...
nejm.org
In the BATURA phase 3b trial, as-needed albuterolâbudesonide resulted in a lower risk of severe asthma exacerbation than as-needed albuterol among participants with disease that was uncontrolled despite treatment for mild asthma. Full trial results and Research Summary: nej.md/43uVpwK
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | New England Journal of Medicine www.nejm.org/doi/abs/10.1...
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | NEJM
Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence t...
nejm.org
Last night at #ISTH2025, we honored a gentle giantâDr. Hau Kwaan, Professor Emeritus at âŠâȘâŠâŹâ©Northwestern. A true #Fibrinolysis pioneer with 400+ articles since the 1950sâstill contributing posters in his 90s. Thanks, Mark Walsh, for a moving laudatio. @isth.org www.linkedin.com/posts/janhar...
Later last night at #ISTH2025, we had the privilege of honoring a gentle giant of the fieldâDr. | Jan Hartmann, M.D.
Later last night at #ISTH2025, we had the privilege of honoring a gentle giant of the fieldâDr. Hau Kwaan, MD, PhD, FRCP, FACP, Professor Emeritus at Northwestern University - The Feinberg School of M...
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Itâs Code Red for Vaccines The number of changes to vaccine policy is dizzying & RFK Jr is just getting started! Dissolving the group of experts that drive policy is declaring war on âwhat wasâ I write in @nytimes.com about what is and is not working www.nytimes.com/2025/06/11/o...
Opinion | Itâs Code Red for Vaccines in America (Gift Article)
How to make sense of all the vaccine policy changes.
nytimes.com
This tiny device can shrink dangerous blood clots. Itâs called the âmilli-spinnerâ and its invention was partly an accidentâŠ
2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP url:https://academic.oup.com/ejcts/article/67/5/ezae352/7815985
jamanetwork.com/journals/jam...
Platelet Transfusion International Clinical Practice Guidelines
This Special Communication discusses the updated Association for the Advancement of Blood and Biotherapies and the International Collaboration for Transfusion Medicine Guidelines international clinica...
jamanetwork.com