Pablo Marcos-Manchón

@jazzmaniatico.bsky.social

ML Engineer trying to do neuroscience

Very cool: it's amazing that this doesn't rely on paired data! @mickbonner.bsky.social and I recently found that the shared geometry is characterized by a ~universal power-law: doi.org/10.1371/jour..., Fig 2 Now I'm curious if we could have done it without the paired stimuli...

Universal scale-free representations in human visual cortex

Author summary The human cerebral cortex is thought to encode sensory information in population activity patterns, but the statistical structure of these population codes has yet to be characterized. ...

doi.org

Are gist-like shifts in memory over time evidence of engram transformation? Really? Or partly a general response bias? At #APS2026 in Barcelona this week, Mattia Delmarco will present our work on object typicality and visual memory. psychologicalscience.confex.com/psychologica...

Typicality Effects In Visual Memory: Co-Occurring Representational Drift and Global Bias

Episodic memory is reconstructive: recollection combines stored perceptual deta...

psychologicalscience.confex.com

In neuroscience, we often try to understand systems by analyzing their representations — using tools like regression or RSA. But are these analyses biased towards discovering a subset of what a system represents? If you're interested in this question, check out our new commentary! Thread:

What do representations tell us about a system? Image of a mouse with a scope showing a vector of activity patterns, and a neural network with a vector of unit activity patterns
Common analyses of neural representations: Encoding models (relating activity to task features) drawing of an arrow from a trace saying [on_____on____] to a neuron and spike train. Comparing models via neural predictivity: comparing two neural networks by their R^2 to mouse brain activity. RSA: assessing brain-brain or model-brain correspondence using representational dissimilarity matrices

🚨 New preprint alert! Excited to share our latest work on alpha/beta activity, eye movements, and memory. Across 4 experiments combining scalp EEG/iEEG with eye tracking, we show that alpha/beta activity directly reflects eye movements, and only indirectly relates to memory. 👇 Highlights (1/7):

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Low-frequency brain oscillations reflect the dynamics of the oculomotor system: a new perspective on subsequent memory effects https://www.biorxiv.org/content/10.1101/2025.07.29.667451v1

🧠 Paper out! We investigated how hippocampal and cortical ripples support memory during movie watching. We found that: 🎬 Hippocampal ripples mark event boundaries 🧩 Cortical ripples predict later recall Ripples may help transform real-life experiences into lasting memories! rdcu.be/eui9l

Movie-watching evokes ripple-like activity within events and at event boundaries

Nature Communications - The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human...

rdcu.be

🧠🚨 How does the brain represent what we see? Is visual input transformed to form these representations in similar ways across people and even AI models like DNNs? We explore these questions using fMRI and large-scale representational alignment analyses. 🔗 arxiv.org/abs/2507.13941 Thread👇 (1/8)

Convergent transformations of visual representation in brains and models

A fundamental question in cognitive neuroscience is what shapes visual perception: the external world's structure or the brain's internal architecture. Although some perceptual variability can be trac...

arxiv.org

Deep learning models and brains share fascinating parallels in their ability to process and instantly integrate new knowledge. Join us this year at ICON 2025 to discuss how sudden learning emerges across artificial and biological systems! 🧠🤖

Johannah Völler@jvoeller.bsky.social · last yr.

📣 ICON Symposium Really excited to announce our symposium at @ICON this year on Sudden Learning Across Systems! Together with lots of cool people: @gonzalezgarcia.bsky.social @lindedomingo.bsky.social @ortiztudela.bsky.social @anikaloewe.bsky.social @jazzmaniatico.bsky.social and Andrea Greve!