A one minute primer on how #AutoSpectral improves spectral flow cytometry unmixing by using per-cell calculation of autofluroscence spectra. Use our R package and get higher quality spectral data, easy as that! www.biorxiv.org/content/10.1...

Excited to share our work published in @cp-immunity.bsky.social! We investigated the role of HIF-1α in CD4 T cells using #Xenium spatial transcriptomics in infected lungs containing #TertiaryLymphoidStructures (TLS) (1/10). www.cell.com/immunity/ful...

HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung

Tertiary lymphoid structures are critical components of tissue immunity, necessitating better understanding of their organization and immune functions. De Lima et al. investigate the spatial and tempo...

cell.com

Excited to share our new preprint on Hif1a in lung CD4 T cells ⏲️🥧 It’s been a challenging but rewarding journey. Huge thanks to Carolyn for her brilliant mentorship and to all our collaborators for their support!

Carolyn King@immunologyking.bsky.social · last yr.

We've worked on Hif deletion in CD4 #Tcells for an embarrassingly long time. We gave up and had to rederive the T conditional KO mice after we stumbled on a phenotype in # NK cells from these mice (1+ years after data acquisition) It's been long, slow and fascinating. In a nutshell...

🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues. 📍 Where: Basel, Switzerland 📅 When: 26th–29th August 2025 📝 Registration deadline: 30th May 2025 Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social #EMBOBarrierTissues

Adaptive immunity in barrier tissues

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

meetings.embo.org

Time course of the classic CCL19, CCL21, AND the more recent role of Ch25h in lymphocyte dynamics. Particularly intriguing to see Ch25h’s influence beyond mucosal sites. Fascinating work!

Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes

Sustained lymphocyte migration from blood into lymph nodes (LNs) is important for immune responses. The CC-chemokine receptor-7 (CCR7) ligand CCL21 is…

sciencedirect.com

Excited for an amazing meeting in Basel, CH ❤️‍🔥 So much to learn, share, and enjoy!

Carolyn King@immunologyking.bsky.social · 2y ago

Registration is live!! May 30th deadline for #EMBOTissueImmunity in Basel🇨🇭 (home to Eurocup 2025, Eurovision 2025, Art Basel, world renowned architecture and muuuuuch more!) Be our guest for groundbreaking #immunology discussion, swimming & fun along the Rhine. meetings.embo.org/event/25-bar...