AI meets #CancerResearch: Researchers from LOEWE CARISMa & @loewe-fci.bsky.social identified biological markers of high-risk diffuse large B-cell lymphoma using interpretable🤖AI. A key step toward earlier risk detection+more🎯personalized cancer treatment. @goetheuni.bsky.social @jenssle.bsky.social

🎉🚀 We're excited to share our latest insights on #DLBCL www.cell.com/cancer-cell/...! 🧵 How can we understand its clinical & molecular heterogeneity by incorporating the proteome?

Pathogenesis of diffuse large B cell lymphoma proteogenotypes

Enssle et al. perform transcriptomic and proteomic profiling of diffuse large B cell lymphoma (DLBCL), revealing seven proteogenotypes (PGs) that reflect molecular and tumor microenvironment features ...

cell.com

First post here, but very happy to share our most recent findings from studying DLBCL at single-cell granularity (www.cell.com/cancer-cell/.... This was a great collaborative effort, and I am honored to have contributed as co-first author. Here's a short recap of the highlights. 🧵👇