Just wrapped up an incredible time at 2025EISG! So many thought-provoking talks and loved connecting with fellow researchers🧑🔬🤯🐭🔬 Grateful for the science, the people, and the energy! @eisg2025.bsky.social @Lickert Lab ;)
Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight | New England Journal of Medicine www.nejm.org/doi/full/10....
Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight | NEJM
Evidence suggests that incretin-based dual agonist pharmacotherapy is helpful in persons with obesity. Mazdutide, a glucagon-like peptide-1 and glucagon receptor dual agonist, may have efficacy in ...
nejm.org
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org