Jesus Castagnetto 🇵🇪 (@jmcastagnetto@mastodon.social)
@jmcastagnetto.bsky.social
Chemist (PhD, NYU '97), Bioinformatics mangler, Biomedical Informatics dabbler, Data artisan, R scribbler, Metalloprotein DB creator, former PHP/PEAR kludger. #Rstats #OpenData #Science #BiomedicalInformatics #DataScience #DataVisualization #OpenSource
For the #font nerds here (I'm just an aficionado): "Designing Michelangelus" microsoft.design/articles/des... #typography
Designing Michelangelus
Inside the making of Michelangelus, a contemporary serif shaped by handwriting, architecture, and stone
microsoft.design
Completely delusional testimony form Sam Altman: "Accept ‘bad things’ in return for benefits of #AI, says Sam Altman" www.theguardian.com/technology/2... #OpenAI #AIBubble #AIPsychosis
Accept ‘bad things’ in return for benefits of AI, says Sam Altman
Boss of OpenAI calls for a regulatory light touch because of the ‘good stuff’ the technology can deliver
theguardian.com
A #DuckDB file doesn't have to contain any data. It can store nothing but view definitions pointing at files stored somewhere else, such as Parquet on object storage. The file stays a few hundred KBs no matter how large the data it describes. In this post, we create such a small shareable catalog:
A DuckDB Database with No Data in It
A DuckDB database file does not have to hold any data. It can store nothing but view definitions that point at Parquet files on object storage, so a few hundred kilobytes behave like a shared catalog ...
duckdb.org
From #Nature: "An open vision-language model for diverse #medical applications" www.nature.com/articles/s41... #AI #Medgemma #LLM #ComputerVision
A good post by Denis Stetskov, about the madness in the #AI industry: "Nobody Remembers the Last Future" techtrenches.dev/p/nobody-rem... ... Prompt engineer, vibe coder, context engineer, loop engineer, graph engineer: each is a job identity with an expiry date ... #jobs #vibecoder #promptengineer
Vibe Coding, Loop Engineering and the AI Buzzword Graveyard
Every few months the AI industry announces the end of how we work, then forgets it and sells a course on the next one. Word, mandate, metric, syllabus, repeat.
techtrenches.dev
#TIL that #Ollama supports local decision models, compatible with the #Typesafe #API ollama.com/blog/ollama-... I now have something to play with next weekend #AI #DecisionModel
Ollama now supports Jev-style decision models · Ollama Blog
Ollama now supports decision models, based on TypeSafe's Jev API for fast, typed decisions. Decision models can now be run at no cost with low latency. Based on text, decision models answer yes-or-no ...
ollama.com
A very interesting post on how #OpenAI was breached: "Hacking OpenAI" www.hacktron.ai/blog/hacking... '... A heap overflow and SSO misconfiguration to compromise OpenAI internal repositories ...' #Security #AI
Hacking OpenAI
A heap overflow and SSO misconfiguration to compromise OpenAI internal repositories
hacktron.ai
#UNESCO has opened a new call for young (under 40 yr old) researchers in #STEM: unescoalfozanprize.org/about/ #Science #research
About | UNESCO AL FOZAN International Prize for the Promotion of Young Scientists in STEM
unescoalfozanprize.org
#TIL from #MIT Tech Reviews that #OpenAI is funding #research in #Biomedicine and #PublicHealth: " #AI models need more #data about #biology, and OpenAI is paying to create it" #Health www.technologyreview.com/2026/09/15/1...
AI models need more data about biology, and OpenAI is paying to create it
The OpenAI Foundation is funding a new effort called Data for Public Health.
technologyreview.com
The National Academies of #Science, Engineering, and Medicine (#NASEM, #USA) has published the latest version of "On Being a #Scientist - A Guide to the #Responsible and #Ethical Conduct of #Research" (Fourth Edition) nap.nationalacademies.org/pubs/29488/ #Science #ethics
On Being a Scientist: A Guide to the Responsible and Ethical Conduct of Research: Fourth Edition
Explore the fourth edition of On Being a Scientist, a guide to responsible and ethical conduct across the research enterprise.
nap.nationalacademies.org
Reading this piece on #OpenAI, about the bad/strange/unexpected behavior of their #LLM models, I ended up with the feeling that these models behave like #teenagers: they need precise instructions, but they do what they want and try to rebel. #AI #misalignment www.theguardian.com/technology/2...
OpenAI reveals cases of ‘concerning’ AI behaviour as it announces new disclosure system
Model adopting ‘jailbreak-like instructions’ among six more cases as firm reveals framework for tracking AI misalignment
theguardian.com
#Nature: "Reimagining #research papers as interactive and reliable #AI #agents" www.nature.com/articles/s41... '... Here we introduce Paper2Agent, an automated framework that converts research papers into artificial intelligence (AI) agents ...' #Science
Reimagining research papers as interactive and reliable AI agents - Nature
Paper2Agent converts research papers into interactive artificial intelligence agents by turning manuscripts, code and data into model context protocol-based tool-invoking systems that reproduce origin...
nature.com
#TIL about this great video from the #Consumer Council of #Norway "The Life of Death and the Ensh*ttificator" www.youtube.com/watch?v=d6SP... #Enshittification
The Life of Death and the Ensh*ttificator
YouTube video by Forbrukerrådet - Norwegian Consumer Council
youtube.com
#UN: "Türk calls for urgent, meaningful action to tackle unprecedented #AI #risks" www.ohchr.org/en/press-rel... ... “We are on the cusp of irreversible change, affecting not just us but generations of humanity to come,” the High Commissioner said in a letter addressed to States and AI developers
Türk calls for urgent, meaningful action to tackle unprecedented AI risks
GENEVA – UN Human Rights Chief Volker Türk on Monday called on States and the world’s ‘frontier’ artificial intelligence companies to act urgently to ensure meaningful AI governance keeps pace with it...
ohchr.org
#TIL about a platform to explore #USA #Energy #data, created by the #OWID folks: #OpenData usenergydata.org
Understanding America's energy system
Track and understand the numbers behind US energy — year by year, and state by state.
usenergydata.org
A good post by @doctorow.pluralistic.net: " #LLMs are real, #AI is fake", about all the madness and hallucinations of the people in AI companies, who (IMHO) tend to anthropomorphize the actions of the stuff they make pluralistic.net/2026/09/12/g...
Pluralistic: LLMs are real, AI is fake (12 Sep 2026) – Pluralistic: Daily links from Cory Doctorow
pluralistic.net
The #UN assembly adopted the 'Equal Earth' projection as official #map representation. #USA was the only vote against. #GIS #EqualEarth press.un.org/en/2026/ga12...
#TIL about a tool (in #Spanish) to generate #LinkedIn #Slop that, unfortunately, does read like stuff from that site: infladin.theshockcoffee.com
Inflad-ín — Inflá lo que te pasó
El traductor de humano a LinkedIn, hecho con cafeína y cero humildad.
infladin.theshockcoffee.com
"Attacker stole a METR API key, used $600K worth of credits, and no one noticed for weeks" #AI #Security #VibeCoding https://www.theregister.com/security/2026/09/01/attacker-stole-a-metr-api-key-used-600k-worth-of-credits-and-no-one-noticed-for-weeks/5293730
#TIL about the #vintage #AI collection from the #Internet #Archive archive.org/details/vint... #InternetArchive
Vintage Artificial Intelligence
A curated collection of early computer software claiming some aspect of artificial intelligence as a primary feature, allowing the early interactions of humans and machines before things got a little ...
archive.org
More #AI #agent #vulnerabilities "#Claude, #Codex, and #Hermes installed unowned #code inside corporate networks" (Ars Technica) https://arstechnica.com/security/2026/08/claude-codex-and-hermes-installed-unowned-code-inside-corporate-networks/ #Security
"Researcher shows how #Claude #Code can be tricked simply by asking it to summarize a website" https://www.theregister.com/research/2026/08/28/researcher-shows-how-claude-code-can-be-tricked-simply-by-asking-it-to-summarize-a-website/5293372 #AI #Anthropic #Security #ClaudeCode #Vulnerability
"Two WA men charged following AFP-FBI-WAPF disruption of alleged global #cybercrime syndicate " www.afp.gov.au/news-centre/... #Australia #Security #TeamPCP
Two WA men charged following AFP-FBI-WAPF disruption of alleged global cybercrime syndicate | Australian Federal Police
Two West Australian men have been charged following a joint investigation between the AFP and Western Australia Police Force (WAPF), working in parallel with the Federal Bureau of Investigation (FBI),...
afp.gov.au
"LibreOffice 26.8 brings professional #typography, deeper support for the world's writing systems, and no artificial intelligence" (TDF Community Blog) #LibreOffice #OpenSource #AI #NoAI #AIFree https://blog.documentfoundation.org/blog/2026/08/26/libreoffice-26-8/
#Reuters: #Nvidia agrees to buy Hugging Face for $12.9 billion, The Information reports www.reuters.com/technology/n... #HuggingFace #AI
Nvidia agrees to buy Hugging Face for $12.9 billion, The Information reports
Nvidia has agreed to buy Hugging Face, a repository of open-source AI models, for $12.9 billion, The Information reported on Wednesday, citing a person with knowledge of the deal.
reuters.com
About #DuckDB: "#AWS buys #DuckLabs, the people behind the popular in-process #OLAP #database" https://www.theregister.com/databases/2026/08/26/aws-buys-ducklabs-the-people-behind-the-popular-in-process-olap-database/5292590
A Small language model by a friend of mine and old style hacker: 'Yachay #SLM" https://github.com/unimauro/yachay-slm Documentation in Spanish but code is in python and rust :-) Created to work in regular hardware #AI #Opensource #Python #rustlang
#TIL about this #volunteer effort to restore the #health information and #data that has been lost from the #CDC website: restoredcdc.org/www.cdc.gov/ #PublicHealth
Centers for Disease Control and Prevention
restoredcdc.org
More details on the upcoming #duckdb version: "DuckDB v2.0: Your #Database Deserves a Better #Parser" https://duckdb.org/2026/08/20/duckdb-20-peg-parser #SQL #OpenSource
🤦♂️ " #NIH Wants to Remove Peer Review Scores From #Grant Applications " #science #political #PeerReview https://www.insidehighered.com/news/quick-takes/2026/08/17/nih-wants-remove-peer-review-scores-grant-applications