New preprint from the lab led by Yanyang Chen identifies BAF as a key regulator of TREX1 activity at micronuclei.

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei https://www.biorxiv.org/content/10.1101/2025.04.14.648782v1

@johnmaciejowski.bsky.social we are looking forward to your presentation at #IOSCD25 in Malta🌞 Please share with your followers to let them know early bird registration & talk submission close on 01 May! Find out more: bit.ly/IOSCD25_Talk...

Our new #IOSCD25 series highlights inter-organelle crosstalk through the lens of stress responses - bringing together experts in genome stability, organelle biology, inflammation & disease to spark collaboration & new discoveries🔬✨ Submit an abstract ➡️ bit.ly/IOSCD25_Subm...

Please check out our preprint where we find that mitotic transcription helps ensure ecDNA inheritance through chromosomal tethering: www.biorxiv.org/content/10.1...