#Research by Miguel Martin-Aragon Baudel of @pharmacologyucc.bsky.social and colleagues investigates CaV1.2 dynamics in native male arterial myocytes 🫀 🔬 Read the study here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
The Journal of Physiology
@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
🏆Congratulations to Georgia S Clarke, winner of our 2025 #EarlyInvestigatorPrize in the Inter-organ category! Her prize-winning research provides new insights into how pregnancy and diet influence gut-brain signalling. 📖 Read the study👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
🏆 Congratulations to Philippa Wittenberg, winner of our 2025 #EarlyInvestigatorPrize in the Cardiovascular category! Her prize-winning research provides new insights into how intracranial baroreceptors may regulate blood pressure. 📖 Read more👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Kenth-Arne Hansson of @uio.no shares this #Opinion on a transcription-driven model of scaled myonuclear accretion reveals a quantitative role for nuclear reserve capacity 💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Luke R. Arieta from @umassamherst.bsky.social et al. found that neither intracellular #oxygen availability nor #mitochondrial coupling explain lower oxidative capacity in older human vastus lateralis muscle in vivo 🔎 🔬 Read the paper👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
🏆Congratulations to Wen Tong, winner of our 2025 #EarlyInvestigatorPrize in the General category! Her award-winning paper reveals how placental mitochondria adapt to maintain energy balance during gestational hypoxia. 📖 Read it here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Lee Min Leong and colleagues provide evidence that #interglomerular inhibition generates non-monotonic concentration-response relationships in mitral/tufted glomeruli in the mouse #olfactory bulb 🧠 💉 Read the #research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Read Naoya Murao's #Reply to Huang et al.: ‘Segmental fructose handling may refine the temporal glucagon-like peptide-1/glucagon-like peptide-2 framework during chronic fructose exposure’ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Segmental fructose handling may refine the temporal glucagon-like peptide-1–glucagon-like peptide-2 framework during chronic fructose exposure' Ying Huang and co-authors write this #LettertotheEditor based on the study by Murao et al. (2025) ✍️ ✉️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
The findings from this study by Olivia M. S. Gold and colleagues conclude that amino acid modulation of the #carotid body selectively modulates peripheral chemoreceptor #respiratory reflex 🫁 🔬 Read it here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
🏆 Congratulations to our 2025 #JournalClub Prize winners, Eric B Emanuelsson & Oscar Horwath! Their winning paper explores how to preserve muscle and function during GLP-1-based weight loss treatment. 📖 Read it here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Recent #research by Kento Nakagawa & Rieko Osu found that transcutaneous auricular vagus nerve stimulation during short-term #motor practice drives #cortical plasticity without behavioural improvement ⚙️ 🧠 Read the study👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
🚨 Our latest issue is now live! Featured on the cover: a penetrating arteriole reconstructed from a 3D mouse brain volume, revealing the presence of a focal, voltage-insensitive constriction 🧠 📸 📖 Read the full issue: physoc.onlinelibrary.wiley.com/toc/14697793...
Andrew K. Yegian from @harvard.edu and colleagues present longitudinal and cross-sectional evidence that daily #resting and #activity energy expenditures are independent in humans 🚴♂️🔎 Read the research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
This study by Gretel S. Major and collaborators finds that regimen-dependent #glucocorticoid effects improve #muscle performance without altering CNS physiology in mdx mice 🔬 🔎 Read the research 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Glutamatergic modulation of transcranial direct current stimulation over the premotor cortex combined with peripheral nerve stimulation promotes observation–execution-related #cortical excitability and #motor performance 🧠 ⚙️ By Fengxue Qi et al. 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Human position sense based on memories is not proprioception' In this #Opinion article, Uwe Proske of @monashuniversity.bsky.social and Bernhard M. Weber of @dlr-en.bsky.social discuss human position sense and how it is measured ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Donald L. Peden from @lborouniversity.bsky.social and colleagues found that sprint-interval training with post-exercise blood flow restriction increases #mitochondrial content and #respiration 🔎 🏃 Read the study here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Runji Chen and colleagues observed that #FURIN induces vascular endothelial cell death and #efferocytosis through enzymatic cleavage of thrombospondin-1 🫀 🔬 Read the study here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Combined emission #ratiometry and motion tracking for optical #mapping of contracting hearts: Validation with monophasic action potentials'🫀 Read the latest #Technique article from Vineesh Kappadan and colleagues at @imperialnhli.bsky.social🔗 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Glutamate and GABA in the #carotid body: Expanding the #framework of hypoxic chemoreflex regulation' Silvia V. Conde writes this #Perspective piece on the recent work of Gold and collaborators ✍️ 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
This recent study by Mackenzie N. Kehmeier from @uoregon.bsky.social and colleagues found that APOE4 negates the effects of #ovarian hormones on #cerebrovascular endothelial and mitochondrial function 💊 🫀 Read the #research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this #PhysiologyShorts video, Daphne Jansen, Lucas Mensink, Matto Leeuwis, and Patrick Forbes from @erasmusmc.bsky.social explain their research into cortical responses to balance perturbations and what it reveals about how we stay upright. 📺 Watch the video: www.youtube.com/watch?v=pkQp...
Amino acids partially override inhibitory effects of #octreotide on islet #hormone secretion in healthy individuals 💉 🔬 Read the #research from Josephine Reiche and colleagues👇️ 📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Dirk F. van Helden and colleagues finds that inflammation induced by snake #venoms optimizes #envenomation 🐍 🫀 Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Eloise K. Tarry from @deakinuniversity.bsky.social and colleagues observed that skeletal muscle #proteomics links #mitochondrial abundance with peak fat oxidation in physically active young males 🚴 🔎 Read the research 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Matthew J. Eden from @umich.edu and colleagues present a #microstructurally motivated framework to study #autoregulation in the coronary circulation 🔎 🔬 Read the #Research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Is #oxysterol accumulation a central physiological trigger of #inflammaging?' Read this #Opinion by Nila Ganamurali and Sarvesh Sabarathinam 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
Eric T. Hedge and colleagues investigated the influence of sex and heart size on #cardiovascular adaptations to 2 years of endurance #exercise training in sedentary middle-aged adults in this recent study 🫀 🏃 Read it here🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this recent study, Lotte J. A. M. Razenberg of @amsneuroscience.bsky.social and colleagues conclude that integration of #cortical inputs in the lateral #hypothalamus is dominated by the medial prefrontal cortex 🧠 🔎 Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...