Jan T Kielstein, MD
@jtkidney.bsky.social
2nd generation #kidney doctor with a passion to make #dialysis #bloodpurification technology available to all in need. #GENIUS for green dialysis.
The #NephJC interns @manoleaandreea.bsky.social and @divyaveerssneph.bsky.social dissect the FINDCKD study from @brendonneuen.bsky.social et al www.nephjc.com/news/2026/7/...
Beyond Diabetic Kidney Disease: FIND-ing Finerenone's Next Role — NephJC
FIND-CKD extends finerenone beyond diabetic kidney disease, showing slower eGFR decline and sustained albuminuria reduction in non-diabetic CKD. While the benefits are modest and cardiovascular effect...
nephjc.com
„Sometimes a road less travelled is less travelled for a reason.“ at least according to Jerry Seinfeld. I think we should more frequently travel the road of occupational health to screen for #CKD. #CKDatWork: screening for CKD in occupational health academic.oup.com/ckj/article/...
#CKDatWork: screening for CKD in occupational health
To the Editor,
academic.oup.com
#ADVOCATE was not only an acronym but a prediction of who would deal with #Avacopan. Funding is needed to conduct studies that address dosing issues and new formulations intubated patients. Our patients need #advocates to fight for treatment options of severe diseases. www.nejm.org/doi/full/10....
RETRACTED: Avacopan for the Treatment of ANCA-Associated Vasculitis | NEJM
The C5a receptor inhibitor avacopan is being studied for the treatment of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. In this randomized, controlled trial, we assigned patient...
nejm.org
@ndt-era.bsky.social was right on publishing a thrice weekly dosing guidance post-dialysis for #Cefazolin in patients undergoing hemodialysis in 1999 academic.oup.com/ndt/article-.... This comes now handy after publication of the #SNAP-trial @nejm.org www.nejm.org/doi/full/10....
Cefazolin serum concentrations with fixed intravenous dosing in patients on chronic hemodialysis treatment
Sir,
academic.oup.com
Extracorporeal blood purification can be useful in intoxication depending on toxicokinetic properties. Maj-Britt Nachtigall and @stephan-aus-b.bsky.social extended the knowledge base on #Chlorprothixene #intoxication treated by high-flux hemodialysis and TPE. karger.com/cnd/article/...
Neither Therapeutic Plasma Exchange nor High-Flux Hemodialysis Enhances the Removal of Chlorprothixene in Case of Intoxication despite a Drop in Plasma Levels: A Case Report
Abstract. Introduction: Chlorprothixene is a typical antipsychotic, primarily used in the treatment of psychotic disorders. Overdose may result in severe cardiovascular and central nervous system toxi...
karger.com
Welcome to scientific bouncing castle # 10 at #ERA26 where #TorstenMeyer presents „ShuntWizard-a new smart application for vascular access self-monitoring in HDpatients. Comparison of AVFsounds recorded by smartphone vs e-stethoscope“ a joint project of #Carealytix and #skbs supported by the #NBank.
#finrenone becomes another pillar of #CKD treatment - that’s the interpretation of the „Efficacy and safety of finerenone in patients with chronic kidney disease: An dividual participant data pooled analysis (INFINITY)“ data presented at #ERA26
Spoiler alert ‼️ Timing is everything. The #NEJM has the #FIND-CKD already online. #GMT is not #CET. www.nejm.org/doi/full/10....
Finerenone in Persons with Chronic Kidney Disease without Diabetes | NEJM
In randomized trials, finerenone, a nonsteroidal mineralocorticoid receptor antagonist, improved kidney and cardiovascular outcomes in patients with type 2 diabetes and chronic kidney disease (CKD)...
nejm.org
Olivier Moranne hosting the 7th edition of the Les Arènes de la Plasmaphérèse at @chudenimes.bsky.social campus with an impressive lineup of #apheresis specialists.
Happy to engage in a PRO /CON discussion on the role of TPE in ANCA vasculitis in a @ucsandiego.bsky.social meeting . ucsd.cloud-cme.com/course/cours...
On the occasion of #World Kidney Day@dgfn.bsky.social members Prof. Eckardt and myself could update the Committee on Health on the @who advised national action plan for early detection and management of kidney disease. It’s time to provide comprehensive, uninterrupted and sustainable kidney care.
My mother in law’s coffee filter featured at the Committee on Health of the #Bundestag. When your coffe filter rips you have grinds in the cup - if your kidney filter breaks you have albumin in the urine. The #UACR is easy to do, cost effective and helps to diagnose #CKD (chronic kidney disease).
And the winner is - Lower Saxony ! Dr. Hauke Wülfrath and collaborators from Braunschweig and Stuttgart performed an important analysis of PD catheter implantation procedures in Germany over a decade. lnkd.in/dEEb5nXB The highest rate of PD-catheter implantation could be found in Lower Saxony.
Prof. Schmidt-Ott and Prof. Klingel opening the 23rd edition of the #apheresis therapy seminar in #Berlin.
From the ice bear Knut to the bedside - Harald Prüss from @bihatcharite.bsky.social on antibody mediated encephalitis and its treatment by #apheresis.
Vega Goedecke from #Medical School Hannover presenting the baseline data from #EXTINCT #postcovid study to treat #MECSF / #Longcovid with #immonoadsorption. The results of this randomized controlled trial will help to answer many questions of this complex disease.
Reinhard Klingel from Apherese ForschungsInstitut - AFI | Apheresis Research Institute reporting long term follow up of #lipoprotein #apheresis at the 23rd #apheresis therapy seminar. For more details read the accompanying paper link.springer.com/article/10.1...
Lipoprotein apheresis results in plaque stabilization and prevention of cardiovascular events: comments on the prospective Pro(a)LiFe study - Clinical Research in Cardiology Supplements
Elevated lipoprotein(a) (Lp(a)) has emerged as an important independent cardiovascular risk factor, and causal association has been accepted with adverse outcome in atherosclerotic disease. Lipoprotei...
link.springer.com
When you combine the research expertise of @helmholtzhzi.bsky.social & clinical expertise of #skbs with the curiosity, energy and brightness of a student you might defend your MD thesis with honors. Congratulations to #Malin-Theres Seffer on her work on seraph 100 @extheramedical.bsky.social
Got #KidneyWk FOMO like @nephroseeker.medsky.social ? We got you covered with daily coverage of the simultaneous publications! www.nephjc.com/news/kidneyw...
Kidney Week in Houston: Day 1 — NephJC
in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis
nephjc.com
@robmentz.bsky.social giving the best overview on treatment of heart failure and CKD I ever heard - and this as a cardiologist at #kidneywk
This disclosure was the most important one I ever heard, it was also a reminder that collecting data on a global level will have an effect on the personal life of patients and their families. Thanks for a memorable talk @saezlab.bsky.social
Congratulations to @rkramann.bsky.social for receiving the ASN-American Heart Association Donald W. Seldin Young Investigator Award.
Great start of #kidneywk but there are several people from around the world missing - best epitomized by the the absence of social media wizzard @nephroseeker.medsky.social. Hope to see you at #ERA.
Up the blood pressure targets to prevent frail patients from going down! Andrew C. Nixon nicely explaining why frail patients do not benefit from SPRINT blood pressure targets.
Harbir Singh Kohli presenting a nice summary of Challenges in Hypertension Management in Patients Receiving Dialysis at #kidneywk
Always nice to meet Olivier Moranne from @chudenimes.bsky.social. Looking forward to the 2026 edition of arenesdelaplasma.org
One way to keep your workforce healthy - care for their kidneys! Happy to present „Evaluating the Economic Impact of CKD on Germany's Health Care System: A 2023 Claims Data Analysis“ at #kidneywk
„IgAN is a B cell disorder“ - quite a statement but great results of the ORIGIN-3 trial. Kind of cheeky of the #FDA to advise against showing eGFR results.
