Reading through the ASAPs at @synthesis1969.bsky.social and boy-oh-boy is the Thieme website a smooth user experience after having dealt with the RSC and ACS shenanigans. #chemchat
Juha Siitonen
@juhesiit.bsky.social
Assistant professor of organic chemistry at Aalto University. Total synthesis, weird nitrogen species, theoretical chemistry, and education. He/Him. Prior: Rice Univ. 🇺🇸, Lund Univ. 🇸🇪, Univ. of Jyväskylä. 🇫🇮 Website: https://etosgroup.fi/
When I started my group some 4½ years ago, I posted a photo of the then brand new balances in pristine condition on Twitter. Someone commented saying they'll give it a year and it'll be covered in gunk "as always in synthesis labs". I'm happy to announce that did, in fact, not happen. #chemchat
Our department is hiring! We teach and do research with undergraduates exclusively. For a PUI, we have very good facilities and instrumentation (400 MHz NMR, six MS). Great colleagues and students — about 1/3 of majors go on to Ph.D. #chemsky @chemjobber.bsky.social jobs.cofc.edu/postings/18244
Assistant Professor of Chemistry and Biochemistry (organic)
Tenure-Track Assistant Professor in Organic Chemistry. The Department of Chemistry and Biochemistry at the College of Charleston invites applications for a tenure-track faculty position beginning in F...
jobs.cofc.edu
Haloxine gets synthesized after nearly 60 years since its isolation! Spearheaded by PhD student Linh, a biomimetic route featuring two domino reactions builds the alkaloid in three steps. This project has been a true rollercoaster! doi.org/10.26434/che... #chemsky #chemchat
Not a huge fan of the new rsc journal layout. Everything seems awfully cluttered :S #chemchat
Our Department of Chemistry and Material Science at Aalto University is hiring a university teacher in chemistry. You must be able to teach in Finnish. Tule meille Aaltoon yliopisto-opettajaksi! Opetustehtävistä merkittävä osa on kandidaattitason laboratorio-opetusta. www.aalto.fi/fi/avoimet-t...
Kemian ja materiaalitieteen yliopisto-opettaja | Aalto-yliopisto
aalto.fi
I really love it when a fresh batch of scXRD structures drops from our collaborators at @uniofjyvaskyla.bsky.social! N–Cl bonds have become our group's workhorse and the structs allow finding really neat trends, here's a snippet from our 2025 paper. #chemchat #chemsky
Ants recognize their nestmates by their distinctive hydrocarbons, including alkenes. Ozone pollution can degrade these alkene compounds, leaving these social insects stranded in a world of strangers . In PNAS: https://ow.ly/qrCn50Yaq1f
Pick up the nearest book. Turn to page 42, post the second sentence. "The energy is given by E = p²/2m + ½mω²x²." (Stephen Gasiorowicz: Quantum Physics)
Markku Norvasuo@markkuno.bsky.social · 7mo agoPick up the nearest book. Turn to page 42, post the second sentence. "Kertomuksemme pyrkii kuitenkin nyt pelkästään välittämään, vähintäänkin, vähemmän lopullisen illuusion: miksi muuten edes tässä höpöttelisimme?" (Georges Perec: Häviäminen)
I just completed all 12 days of Advent of Code 2025! Day 10 Part 2 took a while to figure out. I really like the 12 day format. #AdventOfCode adventofcode.com
First time to happen this year, I accidentally solved for Part 2 of Day 7 first! Just completed "Laboratories" - Day 7 - Advent of Code 2025 #AdventOfCode #ChemistsWhoCode adventofcode.com/2025/day/7
Day 7 - Advent of Code 2025
adventofcode.com
Did I need an electronic dice? Not really! Did I need to reconnect with my childhood hobby of designing and building rather pointless contraptions? Yes!
Turns out microplastics are now sneaking into natural products, too. pubs.acs.org/doi/10.1021/... #chemchat
Myrrhain A: Structural Reassignment Highlights the Relevance of Plasticizer Contamination in Chemical and Bioactivity Studies
The proposed structure for myrrhain A, containing an unlikely 1,2-di-t-butylbenzofuran substitution pattern, was reassigned as a known plasticizer by direct spectroscopic comparison and Computer Assis...
pubs.acs.org
It's that time again: @cenmag.bsky.social 's molecule of the year poll is now OPEN! Check out the contenders, lovingly curated by yours truly from past C&EN stories, and vote for your favorite by Dec. 11 #chemsky #scisky #moty2025 cen.acs.org/synthesis/Mo...
Meet the molecules of the year 2025
C&EN editors’ annual round-up of spectacular molecules we’ve covered in the past year
cen.acs.org
The vast method development uses photochemistry as a guiding light through many steps in the synthesis of complex target molecules. General concepts with recent examples on the use of photochemistry in natural product synthesis are discussed. Thanks to Elina! #ChemSky pubs.acs.org/doi/10.1021/...
Harnessing Photochemistry in Natural Product Synthesis: From Strategy to Applications
Photochemistry and total synthesis are deeply rooted in the history of organic chemistry, each developing independently while also intersecting frequently. Indeed, mild reaction conditions, versatility of transformations, and complementary selectivities to thermal methods make photochemistry an especially powerful tool for the synthesis of complex target molecules. In this Review, we highlight recent examples of total syntheses (from 2020 to 2025) featuring photochemical reactions as pivotal steps. Although the application of photochemistry in total synthesis has been consistently reviewed throughout the past decades, we feel that the wider emergence of photocatalytic methods, together with the continued importance of certain direct irradiation approaches, warrants its own discussion. We hope that our analytical approach and strategic insights will help us to identify cases where photochemical reactions could prove useful, thereby further encouraging their use in total syntheses.
pubs.acs.org
National Finnish chemistry olympiad exams for 2025 are now prepared and ready for the eager students to solve! En route to #IChO 58!
Our two-step total synthesis of monoterpene lactones Lappaceolide A and B appears in Org. Lett. ASAPs! Kudos to our postdoc Rajanish for troubleshooting the tricky domino reaction, and to undergraduate researchers Jenna and Leevi for initial route exploration. #chemsky pubs.acs.org/doi/10.1021/...
Biomimetic Total Synthesis of (±)-Lappaceolides A and B
The first total synthesis of lappaceolides A and B is achieved in two steps by using a biomimetic vinylogous-Michael–oxa-Michael domino reaction. The domino reaction proceeds with Cs2CO3 in 1,2-DCE at...
pubs.acs.org
The Magauer lab's full account on the total synthesis of ganoapplanin is out! This is a rare in-depth behind the scenes account that I'll no doubt use in teaching our total synthesis course at Aalto. Well worth a read! chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
Evolution of a Strategy for the Total Synthesis of the Ganoderma Meroterpenoid Ganoapplanin
Herein, the development of the first total synthesis of the Ganoderma meroterpenoid ganoapplanin is presented. Insights from unsuccessful approaches guide the design of an efficient route centered on....
chemistry-europe.onlinelibrary.wiley.com
Hey #Chemsky, Does anyone know the story about acrolein? Like...why it isn't available anymore?
My US-based colleagues, FYI: Finnish Research Council is about to announce a special call to fund researchers abroad to relocate to Finland. By all means this is not intended to lure you into moving to Finland, it just happens to be planned right now by pure chance.
A postdoctoral position, funded by the Leverhulme Trust for up to 36 months, is available to join my group at the University of Edinburgh. The project focuses on biomimetic approaches to natural product synthesis. Deadline: 18th April 2025. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
The School of Chemistry invites applications for a Postdoctoral Research Associate position to work under the supervision of Prof. Andrew Lawrence on a project funded by the Leverhulme Trust. The succ...
elxw.fa.em3.oraclecloud.com
2 PhD studentships available (UK students only). Deadline: 4 April. 1. Machine Learning-Guided Synthetic Strategies for Natural Product Synthesis, with @king-smithgroup.bsky.social www.findaphd.com/phds/project... 2. Biomimetic Total Synthesis of Natural Products www.findaphd.com/phds/project...
Machine Learning-Guided Synthetic Strategies for Natural Product Synthesis at University of Edinburgh on FindAPhD.com
PhD Project - Machine Learning-Guided Synthetic Strategies for Natural Product Synthesis at University of Edinburgh, listed on FindAPhD.com
findaphd.com
Hitting the target! Here is our recent review in Euro J Med Chem highlighting the uses and advantages of the very versatile Dimroth Rearrangement in both drug discovery and process chemistry. @uniuef.bsky.social, @elsevierconnect.bsky.social, #chemsky - Check it out - doi.org/10.1016/j.ej...
Check out our latest work on aminochlorination chemistry in Chem. Eur. J. N,N-dichlorocarbamates function as a operationally simple platform for generating N-centered radicals with blue light! @aalto.fi #chemsky doi.org/10.1002/chem...
