Read our new paper! We show how the protease BepA binds the BAM complex and undergoes striking conformational changes, embedding its water-soluble lid into the membrane to cleave outer membrane proteins. www.nature.com/articles/s41... #cryoEM #astburycentre

BAM-BepA complexes in outer membrane protein quality control pubmed.ncbi.nlm.nih.gov/42426009/ #cryoEM

I’m very happy to share my first paper on the effects of AWI interactions and flexibility on SPA data quality! Thank you to everyone on the team 🤩 www.sciencedirect.com/science/arti...

Untangling the effects of flexibility and the AWI in cryoEM sample preparation: A case study using KtrA

Single particle cryo-electron microscopy (cryoEM) is a powerful tool for elucidating the structures of biological macromolecules without requiring cry…

sciencedirect.com

Hey Bluesky! For my first post thought I'd share this awesome movie made by Phopho Biomedical Animation for our recent paper on the folding of bacterial outer membrane proteins in Nature Comms: doi.org/10.1038/s414... #cryoEM #AstburyCentre