KCL Type 1 Diabetes Grand Challenge

@kcltype1diabetes.bsky.social

Official page of our King’s College London project, supported by the Type 1 Diabetes Grand Challenge. We’re developing stem cell-based insulin-producing cells to help restore natural blood sugar control. Excited to share our journey with you!

The KCL Type 1 Diabetes Grand Challenge team concluded the summer at the Annual Meeting of the European Association for the Study of Diabetes (EASD)! One of the team’s abstracts was awarded the Best Early Career Researcher Abstract prize. Stay tuned for more updates on our upcoming publications!

🔬 Researcher Spotlight of the Week: Meet Ryea Arora! Ryea graduated from King’s with a First class MSci in Pharmacology. Ryea works both in vitro and in vivo to help improve the function and survival of stem cell-derived islets. Outside of the lab, you can find Ryea travelling, reading or baking!

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🔬 Researcher Spotlight of the Week: Meet Dr. Zekun Lyu! Zekun completed his PhD at King’s last July. He uses bioinformatics tools to unravel the transcriptional networks within mouse, human and stem cell-derived islets. Outside the lab, Zekun is a keen cook and a big fan of esports and gaming.

Tzuwen from our team was recently hosted by The Sugar Science to talk about her recent paper describing how secretions from supportive cells help improve beta cell function and survival. 🔬🧫 Watch the full talk here (youtu.be/sQbBI2c3GkU?...) and read the paper here (www.mdpi.com/2073-4409/15...)!

Beneficial Effects of Mesenchymal Stromal Cell-Derived Extracellular Vesicles on Beta-Cell Survival

YouTube video by The Sugar Science

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Our technical team won a Freezer Challenge Prize! The Freezer Challenge awards points efficient and sustainable use of cold storage. This year, we improved inventory systems and reduced the number of cold storage units in the department, saving energy and more efficiently using existing storage.

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🔬 Researcher Spotlight of the Week: Meet William Blackstone Whines! William’s research investigates how survival of lab-grown islets can be improved, especially looking at their function in vivo. When not in the lab William enjoys being outdoors, whether this be skiing or just going for a walk.

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🔬Meet Sarah Gatward! ✨ Sarah, our PPI lead and co-applicant, is a Diabetes UK medallist who has lived with type 1 diabetes since March 1972, offering insight from lived experience. Outside research, Sarah is the Finance Director at Yvonne Arnaud Theatre, and enjoys yoga and theatre performances.

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Last week, Aileen, Lydia, and Tzuwen attended the Islet Study Group 2026 conference in Barcelona! Lydia and Tzuwen presented posters describing their research on improving islet function and after a long day of engaging scientific talks the team enjoyed some delicious food and a trip to the beach!

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Last month, our Type 1 Diabetes Grand Challenge Team enjoyed a well-deserved sunny Away Day! ☀️👒 They set off on a 15km walk along the Thames Path from Battersea Power Station to Kew, giving them the chance to slow down, bask in the sunshine, and spend time together outside the lab. 🌳✨

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Our T1DGC-funded early career researchers did us proud at the Diabetes UK Professional Conference 2026 in Liverpool, with excellent presentations from Lydia (received the Early Career Investigator Award), Tzu-Wen (was named Runner Up for the Basic Science Poster Award), Jess, Rosie, and Will!! 🧑‍🔬🎉

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Here’s Aileen giving our lovely Operations Officer, Sula, blessings at her traditional Bangle Ceremony for her baby-on-the-way! ✨ Family and friends blessed her by applying sandalwood to her face and adorning her with colourful bangles, wishing her a safe pregnancy and healthy arrival of the baby.

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