Our new work is out! HS-AFM × MD -->> new insights into multivalent TF–ribosome interactions. pubs.acs.org/doi/10.1021/...
Multivalent Interactions between Chaperone and Ribosome-Nascent Chain Complex Revealed by High-Speed AFM and MD Simulations
Trigger Factor (TF) is a primary ATP-independent molecular chaperone in bacteria that engages nascent polypeptide chains emerging from the ribosomal exit tunnel to assist their folding. However, the r...
pubs.acs.org
Real-time Visualization of Trigger Factor on Translating Ribosomes https://www.biorxiv.org/content/10.1101/2025.05.16.654432v1
Sara M. Alicante presenting her results on Kv7.4 voltage sensor activation during channel gating and how redox regulation affects its behavior at the Biophysical Society Meeting in Los Angeles #BPS2025 #Biophysics #Kv7 #Redox #IonChannels
KCNQ lab has arrived in Los Angeles for the @BiophysicalSociety Meeting! Excited to share our work and engage with the amazing scientific community. See you in the sessions! #BPS2025 #Biophysics
Celebrating a year full of science and achievements within the KCNQ group 🥳 A relaxed dinner to share laughs, lab stories, and, of course, a toast to more discoveries together! 🍷🔬🤯 #TeamKCNQ
Such an engaging presentation by Álvaro Villarroel on redox modulation of Kv7 channels at #IC3TC! Shedding light on their role in neuroprotection. Exciting results on the horizon—stay tuned!👀
www.biorxiv.org/content/10.1... Take a look at our latest preprint! 👀 #CaM #chaperone #co-translationalfolding
Calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel Calcium Responsive Domain
In vivo , the majority of nascent protein chains must begin folding during translation in order to obtain their native structure. While the importance of co-translational folding has become increasing...
biorxiv.org
