Knut Drescher

@knutdrescher.bsky.social

I love science and discovering new things.

Biofilm architecture determines the dissemination of conjugative plasmids: We measured the spatiotemporal spread of plasmids in biofilms and found that plasmids only spread in some biofilm regions! Collab with lab of @sbigot.bsky.social & Christian Lesterlin www.pnas.org/doi/10.1073/...

Biofilm architecture determines the dissemination of conjugative plasmids | PNAS

Plasmid conjugation is a contact-dependent horizontal gene transfer mechanism that significantly contributes to the dissemination of antibiotic res...

pnas.org

🚨🚨 MEGA JOB ALERT 🚨🚨 Independent Group Leader Positions in Computational Biology @humantechnopole.bsky.social! Are you ready to start your own lab? Do you know someone who is? Repost this + share with everyone who might want to know about it. Thanks!!! 🙏 More details below... check it out! 🧵 1/3

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ASM's podcast "This Week in Microbiology" discussed our peptidoglycan danger sensing manuscript in detail: It is a true joy to hear how the paper is perceived through someone else's eyes. The enthusiasm of the speakers is amazing. [From 20 min onwards:] asm.org/Podcasts/TWi...

I Have One Word For You: PETase!

The discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation.

asm.org

We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation. Details here 👇 www.nature.com/articles/s41...

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation - Nature Microbiology

Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

nature.com