Excellent discussions at the 4th annual i4MDS meeting in Milan — advancing immunobiology insights and moving closer to smarter stratification and better treatments for MDS. #i4MDS #EHA #MDS #Hematology #Immunology
Systems Cancer Immunology Group at KCL
@kordastil.bsky.social
The main focus of our research group, also known as the Kordasti Lab, is the role of the immune system, particularly Tregs, in Bone Marrow Failure syndromes and MPN.
New paper out! ✨ We built a humanized mouse model of JAK2-mutated MPN by embedding patient MSCs & progenitors in a gelatin scaffold to recreate bone marrow. It preserves disease genetics and enables research on inflammation, immune control & new immunotherapies. 🔗 Link in first comment
I’m delighted to share our latest work on severe aplastic anaemia, published in Nature Communications. Using advanced single-cell approaches to dissect immune-mediated marrow failure before and after immunotherapy. A great collaboration with NIH. www.nature.com/articles/s41...
Human autoimmunity at single cell resolution in aplastic anemia before and after effective immunotherapy - Nature Communications
The transcriptional phenotype of immune cells associated with severe aplastic anaemia (SAA) may change post immunotherapy. Here the authors analyse single cell transcriptomics of hematopoietic and imm...
nature.com
On May 19th, I’ll be in Stockholm, invited by the Karolinska Institute, to give a talk on the role of the immune system in bone marrow failure syndromes— and how recent findings are shaping the way we treat these conditions. Join is if you’re in Stockholm. news.ki.se/calendar/her...
HERM seminar series - “Beyond the Blast Count: Immune Landscapes and New Frontiers in Bone Marrow Failure"
HERM seminar series at the Department of Medicine, Huddinge.
news.ki.se
Excited to take on the role of Research Lead for the School of Cancer & Pharmaceutical Sciences @KingsCollegeLon. Looking forward to collaborating with brilliant colleagues to drive impactful, translational research and meaningful public engagement. #Research #Collaboration #CancerScience
Had a great time speaking at SFH in Paris on targeting inflammation in MDS. Loved the discussion on patient stratification by mutations & immune subgroups. Thanks to Lionel Adès for the kind invite — excited for more via the #i4MDS consortium!
I had two productive days at the TUD Medical Centre in Dresden, Germany. Great discussions took place regarding current and future collaborations. I also gave a talk on the role of Tregs in bone marrow failure. Looking forward to expanding our project within the KCL-Dresden TransCampus initiative.
King's Ranks Among World's Best in 42 Subjects. The QS World University rankings by Subject, is an extensive overview of international higher education performance, with over 1,700 institutions ranked across 55 narrow subjects and five broad subject areas. www.kcl.ac.uk/news/kings-r...
King's Ranks Among World's Best in 42 Subjects
King's College London celebrates a number of successes in QS Worldwide University Rankings 2025.
kcl.ac.uk
Recenty, we had our annual #i4MDS meeting in The Hague. Great discussions with colleagues about the role of the immune system in MDS and novel findings. Three years ago, when we founded this group, I never expected this level of progress and collaboration. Truly delighted.
