Excited to share our article in the Jean Futrell Memorial issue of #IJMS describing the capabilities of a tandem rotating wall mass analyzer for mass-selecting ultrahigh-m/z ions. www.sciencedirect.com/science/arti... Free access until August 29, 2026 authors.elsevier.com/a/1nMo24xT2v...

Excited to share our paper in the Livia S. Eberlin special issue of #JASMS, where we describe the capabilities of nano-DESI for automated imaging of multiple tissue sections using a microfluidic probe and a robotic sample handling system. pubs.acs.org/doi/full/10....

A Robotic Sample Handling Platform for Fully Automated Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging

Recent advances in mass spectrometry imaging (MSI) have enabled high-throughput experiments, making it possible to image multiple samples and perform three-dimensional molecular mapping. For these app...

pubs.acs.org

Excited to share our paper on the effect of deuterated solvent on the efficiency of singlet oxygen reaction with C=C bonds in lipids for isomer-selective imaging, which is now published online in #ACA. www.sciencedirect.com/science/arti...

Congratulations to Nazifa Wali on her excellent presentation at #ASMS2026!

Check out our latest in Analytical Chemistry. We have developed a workflow for generating an information-rich list of MRM transitions for MS/MS imaging of specific lipid classes: pubs.acs.org/doi/full/10....

Tandem Mass Spectrometry Imaging of Low-Abundance Ether Phospholipids Guided by Bulk Lipidomics Analysis

A central challenge in mass spectrometry imaging (MSI) of lipids is detecting and identifying species overshadowed by higher abundance isobaric lipids. Although tandem mass spectrometry can differentiate many lipid isobars and some isomers, the diversity and heterogeneity of lipids observed in MSI experiments necessitate the development of targeted approaches to differentiate and localize species with an overlapping m/z. To address this challenge, we leverage the fast acquisition speed of multiple reaction monitoring (MRM) to identify and localize hundreds of lipids in a single MSI experiment. We present a workflow to generate comprehensive, system-specific, and information-rich MRM transition lists for MSI and use them to examine the spatial localization of specific lipid classes with nanospray desorption electrospray ionization (nano-DESI) MSI in MRM mode. The lists are generated by integrating information from the LIPID MAPS database with data-dependent acquisition (DDA) and filtering by examining MRM signals of the corresponding tissue lipid extract. Using 165 MRM transitions in a single nano-DESI MSI experiment, we examined the localization of plasmalogen species, their isomers, and corresponding isobars in mouse brain tissue with sn-chain-level annotation. This workflow, which can be readily adapted to other lipid classes and tissue types, establishes MRM-MSI as a powerful strategy for mapping lipid targets in complex tissues.

pubs.acs.org

Please welcome Dr. Sara Amer - PhD #12 from our group! Congratulations on a great thesis defense and on earning your PhD!

Mushfeqa is presenting her work?at #ASMA2026 on the molecular signatures of diabetes studied using nano-DESI imaging.

#ASMS2026 is off to a good start! We are excited to present our work, learn about recent developments in the field, catch up with our friends, and meet new people!

Here are our Monday presentations at #ASMS2026. Come to Mushfeqa's talk and posters by Alyssa, Renkai, and Anthony to learn about the latest developments in nano-DESI mass spectrometry.

Come talk to Erik Sveen about his work at the undergraduate student poster competition tonight at #ASMS2026!

Here is what my group will be presenting at #ASMS2026. Come listen to our talks, visit our posters, and attend the Wed imaging workshop! See you all soon in San Diego!

Excited to welcome 1st year graduate students to the group: Please, meet (from left to right) Naina Beishembieva, Josh Koval, and Yuna Chen. The future is looking bright!

Excited to share our latest paper in ACS Chemical Neuroscience, in which high-resolution nano-DESI imaging is used to study lipid accumulation around the plaques in an Alzheimer's disease mouse model. pubs.acs.org/doi/full/10....

Multimodal Nano-DESI Mass Spectrometry Imaging Reveals Phospholipids Accumulation in and around Amyloid Plaques in Alzheimer’s Disease

Alzheimer’s disease (AD), characterized by β-amyloid plaques, is increasingly recognized by lipid dysregulation as a key factor in its pathology. Mass spectrometry imaging (MSI), a powerful tool for m...

pubs.acs.org

The special issue of #IJMS honoring Jenny Brodbelt, the recipient of the 2024 Thomson Medal, is shaping up nicely. Check out this excellent article collection. Thank you to Amanda Hummon for organizing this issue! www.sciencedirect.com/special-issu...

Check out this exciting perspective article by Thanh Do in the Young Scientist Feature of #IJMS, in which he discusses what can be really measured using ion mobility spectrometry. www.sciencedirect.com/science/arti...

Excited to share our latest paper in Analytical Chemistry describing the use of a confocal distance sensor for constant distance mode mass spectrometry imaging. Congratulations to Tommy Zhang and co-authors on the publication! pubs.acs.org/doi/full/10....

Excited to share our paper in Nature Protocols describing the fabrication of microfluidic nano-DESI probes. Congrats to Lixue Jiang and co-authors! rdcu.be/eqKmk

High-spatial-resolution mass spectrometry imaging of biological tissues using a microfluidic probe

Nature Protocols - We present a protocol for the design, fabrication and use of a microfluidic probe for nanospray desorption electrospray ionization mass spectrometry imaging (nano-DESI MSI) that...

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Congrats Professor Laskin @lablaskin.bsky.social‬ on the review in @natrevchem.nature.com Read more: www.chem.purdue.edu/media/news/2...

Many thanks to Kelly @kmhines.bsky.social and Julia @lablaskin.bsky.social for hosting Ladies wine and cheese night at #ASMS2025! So much fun get together @femalesinms.bsky.social @asms.org ❤️🍾🧀🌸🌹

Another busy day for us at #ASMS2025. Come to our posters to learn about new methods and applications in nano-DESI imaging and ion mobility spectrometry in nano cluster research.

Check out our presentations at #ASMS2025 highlighting our recent efforts in preparative and imaging mass spectrometry, ion mobility, gas phase ion chemistry, and new approaches for studying electrochemical reactions using MS.

On our way to Baltimore! Looking forward to reconnecting with friends and colleagues, learning about the latest in mass spectrometry, networking, and making new connections at #ASMS2025!

✈️ ASMS 2025 Early Career Researcher Travel Awards ✈️ 📢 Call for Applications 📢 Don’t miss this opportunity! Applications are open from *May 12th to 23rd* 📧 hispanicsandlatinxinms.org/asms-2025-ea... #ASMS2025 #MSCommunity

Saddened to share the news that Amina Woods passed away on March 31. Amina was an outstanding scientist who consistently challenged conventional thinking in her field. She inspired many of us through her work and will be deeply missed.

Amina Woods Obituary - Visitation & Funeral Information

Share Memories of Amina & Support the Woods Family

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Check out the latest editorial article in #IJMS, highlighting two exciting perspective articles by Ian Webb and Ahmed Hamid in the Young Scientist Feature collection.

Check out our latest paper on isomer-selective lipid imaging using a singlet oxygen reaction with C=C bonds. We describe a universal photosensitizer compatible with both positive and negative ionization modes. Congrats to Sara Amer and co-authors!

Congratulations to Emily Halpern (A. Laskin Group) on receiving the 2025 Excellence in Collaborative/Industrial Research (ECIR) Award from Purdue's analytical chemistry division!

Congratulations to Michael Espenship (J. Laskin Group) on receiving the 2025 Excellence in Collaborative/Industrial Research (ECIR) Award from Purdue's analytical chemistry division!

Congratulations to Jaskiran Kaur (Kenttamaa Group) on receiving the 2025 Thomas Keough Award from Purdue's analytical chemistry division!

We are pleased to recognize our amazing graduate students! Congratulations to Gwendylan Turner (Simpson Group) on receiving the 2025 Guy Mellon Award in Analytical Chemistry from the analytical chemistry division at Purdue!