Our EvoWeaver work is now included on the Computational and Theoretical Biology focus page of Nature Communications! The page highlights recent work that reports methodological advances in computational biology. www.nature.com/collections/...

Computational and Theoretical Biology

As we navigate the era of big data in biological research, advanced computational techniques, such as mathematical models and machine learning algorithms, are ...

nature.com

Proud to announce a new publication from the lab: EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41...

EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications

Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....

nature.com

🧪🧬🖥️ new paper: Tandem Repeats Provide Evidence for Convergent Evolution to Similar Protein Structures (doi.org/10.1093/gbe/...). You can also see the video explainer here: wrightlabscience.com/publications

Tandem Repeats Provide Evidence for Convergent Evolution to Similar Protein Structures

Abstract. Homology is a key concept underpinning the comparison of sequences across organisms. Sequence-level homology is based on a statistical framework

doi.org

Nishant just came back from the EMSL at PNNL! wrightlabscience.com/news#oct2024

One of our recently published articles has gotten traction in the popular press: www.thehindu.com/sci-tech/sci...

Vancomycin may not be able to treat MRSA infections for long

Researchers have found Staphylococcus aureus can adapt to vancomycin while overcoming its fitness cost, threatening the long-term use of vancomycin in the clinic.

thehindu.com

New Paper Alert! VRSA can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability, from our Master's student (and his second paper published this month!). www.wrightlabscience.com/publications

One of the M.S. students got 2 papers accepted within days of each other! Here is one of them about #MachineLearning, #ElectronicHealthRecord Data, and #AntibioticResistance. #Bioinformatics has such a great place in our evolving healthcare landscape. 🧪 🧬🖥️

We are at #ISMB2024! Come say hi! (I'm probably the tallest person at the conference)

Updates to DECIPHER! It's now DECIPHERv3, with some cool updates! See wrightlabscience.com/news #bioinformatics #bioconductor #Genomics #biotechnology #R

One of the lab members was awarded funding to enhance and maintain #R #Biostrings. We're looking forward to seeing what he can do for the #bioinformatics community.

Cool new paper released from the lab: Many purported pseudogenes in bacterial genomes are bona fide genes! wrightlabscience.com/publications

Hi All: We're looking for Post-Docs for our soggy lab for September. You don't have to already be a bioinformatician, as we are willing to train. We're especially interested in solving antibiotic resistance. Pls reach out w/ questions and share. We'd love to fill this position (we have 2). 🧪🖥️🧬

GLBio24 is in Pittsburgh this year! Submissions are open! Submit to our "Big Biological Data" Special Session! 🧪

Now that Spotify Wrapped has wrapped. Let's check out the Wright Lab Year In Review! 🧪

Turns out that popular AI suggests us not once, but 3 times for the same query on sequence alignments. www.wrightlabscience.com/index.html

We're the Wright Lab at the University of Pittsburgh School of Medicine. We do evolution of antibiotic resistance in a 'soggy' (both dry and wet lab work) lab. Our under-construction website: www.wrightlabscience.com/p/index.html. We also have available T15 funding!

Daniel Bolnick@danielbolnick.bsky.social · 3y ago

Let's start a thread of faculty in evolutionary bio & ecology who are seeking grad students in the run-up to application season. Repost with: who you are, a potential student project, a photo, and a link.

Our department is recruiting PhD students for the 2024 cohort! Come work with us in biomedical informatics. Our lab works on solutions to antibiotic resistance using computational methods. 🧪🧫🩺

Hi! can we be added to the what's science feed/bioinformatics? @danirabaiotti.bsky.social (Also, thanks for curating!) 🧪. 🖥️ 🧬

Are you an undergrad looking for a grad program in the bioinformatics space? Are you interested in new, evolving problems in antibiotic resistance? We have funding. Come work with us! 🧪