Vousden Lab
@labvousden.bsky.social
We study intrinsic cancer cell metabolism, crosstalk between tumour and stroma in TME, and how cancer affects the whole body, including the influence of primary tumours on distant organs and the interplay between cancers and systemic conditions. @theCrick
Congratulations to our PhD student, Ying Thong Low, for winning 3rd prize in the 2026 Crick Science Writing Prize! The prize was open to Crick researchers, and encouraged writing exciting, informative content about their work for a general audience. Proud of her achievement!
Our group leader, Prof. Vousden, has co-authored a new textbook on cancer metabolism with Prof. Navdeep Chandel and Prof. Ralph DeBerardinis. Check it out! pubmed.ncbi.nlm.nih.gov/39500632/
Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities - PubMed
Cancer cells undergo changes in metabolism that distinguish them from non-malignant tissue. These may provide a growth advantage by promoting oncogenic signaling and redirecting intermediates to anabolic pathways that provide building blocks for new cellular components. Cancer metabolism is far from …
pubmed.ncbi.nlm.nih.gov
Interested in tumour metabolism? 🧪 The Keystone Symposia "Tumour Metabolism: New Frontiers in Diet, Microbiome, and Beyond” is taking place next June. Exciting science and discussions ahead — join us there! #KeystoneSymposia #TumourMetabolism #DietandCancer
We're incredibly proud to share that our PI has been awarded the Clowes Award - the oldest award by @theaacr.bsky.social - in recognition of her contributions to cancer research! She will give her award lecture on April 28, at 5:30 p.m. CT in Chicago. See you there!😎 @crick.ac.uk #ProudVousdenites🎉
American Association for Cancer Research (AACR)@theaacr.bsky.social · last yr.Congratulations to the recipients of the 2025 AACR Scientific Achievement Awards and Lectureships. This year’s distinguished class of awardees will be recognized at #AACR25 in Chicago. www.aacr.org/about-the-aa...
Ludwig Cancer Research was well represented in a recent @cancergrand.bsky.social panel on The Future of Cancer Research, which included CEO and Scientific Director Chi Van Dang, Scientific Advisor @labvousden.bsky.social and Ludwig @mitofficial.bsky.social Co-director Tyler Jacks. #CanSky #OncoSky
Congrats!😍
Martha Zarou@marthamz.bsky.social · last yr.Honoured to be one of the first recipients of the EACR-Mark Foundation Postdoctoral Fellowship award to support my work on pancreatic cancer development at @labvousden.bsky.social @crick.ac.uk🥳 Thanks to everyone for the support during this journey! Exciting research incoming 👩🔬👩🔬👩🔬 #womeninSTEM
Kicking off spring with exciting news! Our postdoc, @marthamz.bsky.social has been awarded the highly competitive EACR-Mark Foundation Postdoctoral Fellowships. Congratulations!👏💐🎉 @helloeacr.bsky.social @crick.ac.uk #Pancreaticcancer #womeninSTEM
EACR - European Association for Cancer Research@helloeacr.bsky.social · last yr.Congratulations to our first EACR-@themarkfdn Postdoctoral Fellowship winners! Julie Mazet, Christina Metoikidou and Martha Zarou 👏 This funding is awarded for a period of three years to support excellent postdoctoral researchers in laboratories throughout Europe. magazine.eacr.org/congratulati...
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Walter W. Chen, MD, PhD@walterwchen.bsky.social · 2y agoChristmas came early with a copy of the new textbook on cancer metabolism from #NoTwitterNav, @labvousden.bsky.social, @rjdlab.bsky.social 🥳 Happy to contribute a section on MITO-IP and other rapid organellar immunopurification techniques for studying organellar metabolism!
Very happy to share the latest preprint from the lab. We find that during cell competition, winners induce an increase in proline metabolism in loser cells, and this drives their elimination through repression of the integrated stress response. biorxiv.org/cgi/content/...
Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition
Cell competition is a quality control acting from development to the adult that eliminates cells that are less-fit than their neighbours. How winner cells induce the elimination of losers during this ...
biorxiv.org
Recent publications from our lab: 1. Invited review on obesity and cancer by Estel Solsona-Vilarrasa febs.onlinelibrary.wiley.com/doi/10.1111/... 2. Update on ROS regulation by TIGAR in PDAC and its communication with the tumour stroma, by Eric Cheung www.pnas.org/doi/abs/10.1... Enjoy the read!
Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment | PNAS
The consequences of reactive oxygen species (ROS) in cancer cells are complex and have been shown to both promote and retard tumorigenesis in diffe...
pnas.org
