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Lea Gaucherand

@leagaucherand.bsky.social

Bats 🦇 Viruses 🦠 RNA 🧬 Immunity ♥️ Postdoc with Sébastien Pfeffer @CNRS Strasbourg studying bat antiviral immunity | PhD with Marta Gaglia @Tufts Boston studying influenza PA-X. she/her.

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Lucie Etienne@lucievirevolte.bsky.social · 2mo ago

Insights into longevity & virus-driven adaptation from Myotis bat genomes International & fantastic collab. with @psudmant.bsky.social @denard.bsky.social Labs ! Major credit to the 2 leading scientists: Juan Vazquez & @lauterbur.bsky.social now with their own labs! You 2 rock! (1/n)

Insights into longevity and virus-driven adaptation from Myotis bat genomes - Nature

Comparative and functional analyses of Myotis bats uncover unique patterns of adaptation in virus-interacting proteins and longevity-associated pathways, linking two hallmarks of bat biology.

nature.com

CIRI Lyon@ciri-lyon.bsky.social · 2mo ago

Félicitations à Lucie Etienne et son équipe, soutenue par le CNRS IRP RAPIDvBAT, le CNRS IRC Univ. Arizona et le CNRS MITI, pour leurs travaux sur la longévité et l’adaptation induite par les virus à partir des génomes de chauves-souris Myotis. 💡: www.nature.com/articles/s41....

Lucie Etienne@lucievirevolte.bsky.social · 9mo ago

📣 *Abstract submission by January 31st* "Host adaptations to viral infections” International Meeting May 10th-13th 2026 @cnrs.fr Station Biologique Roscoff, Brittany, France Register & Join us +amazing international speakers! #CNRS @cnrsbiologie.bsky.social #IRP www.insb.cnrs.fr/fr/evenement...

Rapid host adaptations in response to viral infections

Viruses threaten all living organisms leading to molecular conflicts which have shaped hosts over evolutionary timescales. This meeting seeks to gather scientists from diverse disciplines including genomics, population genetics, innate immunology, virology, and beyond, to explore the evolution, diversity, molecular basis, and dynamics of these conflicts.

insb.cnrs.fr

Lea Gaucherand@leagaucherand.bsky.social · 10mo ago

Our latest paper on bat Dicer! 🦇 we show that Dicer antiviral RNAi activity is context-dependent also in bats 👩‍🔬 Specifically in Myotis myotis nasal epithelial cells, Dicer relocalizes to sites of viral replication upon alphavirus infection, which correlates with a proviral activity of Dicer 🦠

Sébastien Pfeffer@sebpfeffer.bsky.social · 10mo ago

Just in time for Christmas, here is the latest paper from the lab! Great work from @leagaucherand.bsky.social and Hugo Marie, with help from Julie Cremaschi. Funded by @frm-officiel.bsky.social, @agencerecherche.bsky.social journals.plos.org/plospathogen... @cnrsbiologie.bsky.social @unistra.fr

American Society for Virology@amersocvirology.bsky.social · 2y ago

Vaccines work! As measles cases have recently been reported in Alaska, Georgia, New York, Rhode Island and Texas, it's important to remember that prior to the introduction of the measles vaccine in 1963, measles killed 400-500 people and resulted in ~48,000 hospitalizations per year.

Graph showing that prior to 1963 when the measles vaccine was introduced, there were around 300,000-700,000 measles cases per year. Within a few years of the vaccine, the number of cases fell below 20,000/year. There were a blips where cases rose, but shortly after the second vaccine dose was recommended in 1989, annual cases have generally been well below 1,000 cases. In 2000, measles elimination was declared in the US. Now we have sporadic outbreaks that typically spread among unvaccinated people. Chart is from Center for American Progress and is based on CDC data on measles cases.
Liz Neeley@lizneeley.bsky.social · 2y ago

Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences. Every Friday, I debrief you over a drink at buttondown.com/liminalcreat...

Making Sense of It All

Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...

buttondown.com

Petr Svoboda@svobodalab.bsky.social · 2y ago

1/n So, this is out in NAR, finally. The longest, the most expensive and the most challenging project in the lab. Sparked by controversy concerning mammalian antiviral RNAi and our identification of Dicer variant, which is sufficient to increase RNAi. doi.org/10.1093/nar/...

Enhanced RNAi does not provide efficient innate antiviral immunity in mice

Abstract. In RNA interference (RNAi), long double-stranded RNA is cleaved by the Dicer endonuclease into small interfering RNAs (siRNAs), which guide degra

doi.org