We are excited to share our latest research now published in Cell Reports. Together with Hyun Lee and Masato Kanemaki lab, we investigate the mechanism underlying the exclusion of FUS and EWSR1—and show that this process is driven by RNA pol II. #dnarepair #fus #dnadamage #DDR #transcription

Cell Reports@cp-cellreports.bsky.social · 4mo ago

RNA polymerase II drives FUS and EWSR1 exclusion from damaged chromatin

👋Our April issue's out! Cover: Live #chromosome tracking 👉🏼Perspective on #lactylation 👉🏼Review on #MechanicalForces in development 🔬 #MyocardialInfarction #PreclinicalStudy #NeuralStemCells #proteostasis #neurodegeneration #mitochondria #CellDeath #cancer & more! www.nature.com/ncb/volumes/...

Hi Bluesky! I made a 3D chromatin starter pack. Let me know if you would like to be added. go.bsky.app/6tTQdqQ

Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...

We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology. www.nature.com/articles/s41...