Excited we can generate nephron cells for preclinical trials. We will continue to perfect the proximal tubule model and are going deep into understanding nephron injury programs and following up on druggable targets that could solve acute kidney injury and maladaptive repair.
A Nature Communications paper from Nils Lindström's lab at USC Stem Cell identifies key molecular switches that generate distinct cell types within the kidney’s filtering units, or nephrons. The lab is getting closer to making therapeutic kidney cells on demand! stemcell.keck.usc.edu/scientists-u...