Lioba Berndt
@liobanause.bsky.social
RA in Computational Psychiatry & Neuropharmacological Systems • MSc Clinical Neuroscience • BSc Psychology
🧠 New pre-print out: doi.org/10.1101/2025...
Sleep as a window into thalamocortical pathology: generative modeling implicates NMDA receptor hypofunction in 22q11.2 deletion syndrome
Background: 22q11.2 deletion syndrome (22q11.2DS) is a strong genetic risk factor for neuropsychiatric conditions, including schizophrenia, autism, ADHD, and intellectual disability. Sleep disturbance...
doi.org
New preprint: How does Behavioral Activation help with anhedonia in depression? Our new study finds that early reductions in aversive Pavlovian Bias mediate symptom improvement - suggesting a specific cognitive mechanism in realistic treatment settings. Read more here: doi.org/10.31234/osf...
Our recent work TED: The Encyclopedia of Domains showcased by UCL: 365 million domain like structures identified in the AlphaFold DB, 194 million with proposed assignments to CATH superfamilies, plus a catalogue of domain-domain interactions. www.ucl.ac.uk/computer-sci...
UCL-led research reveals new protein map with potential to transform disease research
UCL researchers have developed The Encyclopedia of Domains (TED), a tool mapping millions of unknown protein regions, with potential for breakthroughs in drug discovery and disease research.
ucl.ac.uk