There's been no consensus on how to measure immune aging. Now, a new Nature Medicine Perspective from HIP Co-CSOs Shai Shen-Orr & @tsanglab.bsky.social and colleagues proposes a framework to establish the biomarkers, based on #XPRIZEHealthspan data. 🔬 pubmed.ncbi.nlm.nih.gov/42399672/
Shai Shen-orr has an evocative way of describing the frontiers of science. Here, he links the sextant, which allowed exploration of the seas, to the map of the genome leading to new meds, to our unfolding discoveries of the human immunome: New tools unlocking exploration of uncharted territories.
Human Immunome Project@immunome.bsky.social · 2mo agoHIP Co-CSO Shai Shen-Orr: When the tools finally match the ambition, explorers can stop hugging coastlines and sail into open water. Deciphering the human immunome will unleash that moment for medicine — and a thousand ships are waiting to sail. ⛵⛵⛵ youtu.be/ZrGH5pJ4APg
Our latest HIP Banbury video is especially meaningful to me, given all the time I've spent in Senegal. Check it out at the link below.
Human Immunome Project@immunome.bsky.social · 4mo agoProf. Moustapha Mbow on how mapping immune diversity across populations and countries can help give African scientists have a real seat at the table. Our latest episode from the HIP Banbury Series now live: 🎥https://youtu.be/J8AHWVdONBQ
As @derasmus.bsky.social explains, most AI is a black box. ClimateGPT 3+ is different — open, auditable, and grounded in real climate data. Please join me in voting for it in the @Webby awards! Deadline: April 16. 👉 www.internetarchive.eu/2026/04/02/c...
ClimateGPT is a Webby Nominee. Vote Before 16 April. - Internet Archive Europe
Most AI tools are black boxes. You do not know what they were trained on, who decided what counts as reliable, or whether the answers they produce can be checked against anything. ClimateGPT 3+ is bui...
internetarchive.eu
Cool to see what these pioneers at the forefront of systems immunology think about the impact of AI on their research:
Human Immunome Project@immunome.bsky.social · 9mo agoHear from investigators including HIP Co-CSO @tsanglab.bsky.social on how AI is changing immunology research, what is necessary to move forward, the potential and the pitfalls, and what will remain unchanged as the field journeys into a new era. www.cell.com/immunity/ful...
The advent of precision medicine:
Human Immunome Project@immunome.bsky.social · 10mo agoFascinating new podcast on the immune system as the body's early warning system 🧬 @tsanglab.bsky.social (HIP co-CSO) & David Ewing Duncan explain how a blood test could predict disease before you have symptoms The future of catching things early looks really promising! www.npr.org/2025/11/12/n...
Some excellent perspective from the co-CSO at HIP, Shai Shen-Orr, on closing the growing gap between what we can measure and what we can understand. open.spotify.com/episode/56J8...
How CytoReason is Bridging the Data Insight Gap to Accelerate Healthcare Breakthroughs - Ep. 276
open.spotify.com
Notes on a compelling discussion with @tsanglab.bsky.social Genome = blueprint. Immunome = real-time sensor. The "curse of dimensionality" (millions of data points per sample!) meets AI compression. Result? We can finally map the human immune system at scale. @humanimmunomeproject 🚀
What if a simple blood test could reveal hidden diseases before you feel sick? This first-person experience of from David Ewing Duncan explains what it's like to know the score on your immune health. www.technologyreview.com/2025/10/09/1... #humanimmunomeproject #ai #immunology #bigscience
How healthy am I? My immunome knows the score.
Groundbreaking new tests reveal patterns in our immune systems that can signal underlying disease and tell us how well we might recover from our next cold. I got my results in a text message.
technologyreview.com
truly thrilling work at the frontiers of systems biology and AI.
Human Immunome Project@immunome.bsky.social · 11mo ago"Imagine if we can apply the same approach across the entire world and start to map to capture the true diversity of the human immune system so we can build predictive models and figure out interventions." 🔆 Don't miss David Ewing Duncan's new substack: davideduncan.substack.com/p/welcome-to...
Big news: We've announced the largest #systemsimmunology collaboration in history! Ten world-class research institutes are joining @immunome.bsky.social in a pioneering plan to understand human immune response variability. www.humanimmunomeproject.org/news/human-i... @tsanglab.bsky.social
Decades after eliminating malaria, we had the first locally transmitted malaria case since 1991 in NJ yesterday 🦟 www.gatesnotes.com/when-malaria...
gatesnotes.com
This is a remarkable and historic commitment from Bill Gates to spend down his extraordinary wealth in service of solving real world problems and close the Gates Foundation by 2045. I am so glad to see malaria eradication remain among the top priorities.
A faster rollout of malaria vaccines would save many lives economist.com/middle-east-... from The Economist
A faster rollout of malaria vaccines would save many lives
But someone needs to pay for it—and aid budgets are being slashed
economist.com
The loss of services supported by USAID will affect millions of the world’s most vulnerable people. Here's our statement on how the freeze of US foreign aid assistance will result in humanitarian disaster: www.doctorswithoutborders.org/latest/freez...
Freeze of US foreign aid assistance will result in humanitarian disaster
Loss of services supported by USAID will affect millions of the world’s most vulnerable people
doctorswithoutborders.org
🌎 My latest: On Trump's 3 exec orders about WHO & international aid. "This is a moment of geopolitical shift because the US is making itself less relevant" said @yodifiji.bsky.social @kffhealthnews.bsky.social / CBS kffhealthnews.org/news/article...
What a US Exit From the WHO Means for Global Health - KFF Health News
By withdrawing from the World Health Organization and overhauling aid, Trump’s new executive orders endanger Americans and the globe, researchers warn. The move also cedes U.S. power to other nations.
kffhealthnews.org
Hello #booksky - just finished reading Orbital. It’s a really beautiful book, unlike anything I’ve read before, almost poetic. Highly recommend!
