Comprehensive fate mapping of C. elegans transformed our understanding of development, revealing how coordinated fate decisions generate a complex organism. We take a major step toward extending this vision to mammalian development. www.sciencedirect.com/science/arti...

Comprehensive lineage tracing maps the landscape of cell fate decisions in mouse embryogenesis

A comprehensive cell fate map of mammalian embryogenesis has remained out of reach given the scale, cellular diversity, and non-deterministic nature o…

sciencedirect.com

A few years in the making in the @jswlab.bsky.social with William Colgan, Zack Smith, and the rest of our fantastic team: Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis. Excited to hear everyone's thoughts!

Jonathan Weissman Lab@weissmanlab.bsky.social · 6mo ago

Excited to share a new preprint from the lab led by @lukekoblan.bsky.social and William Colgan in which we describe our efforts to define a quantitative cell fate map of mouse embryogenesis! www.biorxiv.org/content/10.6...