Interested in #Mechanobiology #BoneRegeneration and #GrowthFactor mimetics? Check out our paper in Small @wileyonlinelibrary.bsky.social by @finbariii.bsky.social. We show that viscosity unlocks the osteogenic activity of BMP-2 mimetic DWIVA @theglasgowcemi.bsky.social @uofgengineering.bsky.social 🧪

Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA

Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP-2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that....

onlinelibrary.wiley.com

Congrats again!!! Great work @nadiasoulioti.bsky.social @delphe.bsky.social 🥳🥳

🦋 Gourdon Lab 🦠🔬@delphe.bsky.social · 10mo ago

🚀Huge congrats to @NadiaSoulioti.bsky.social on passing her PhD viva yesterday! I’m so proud of you! 🥳🎉 🧪Thanks to the exam panel: Andrew Hoy (UNSW Sydney, external), @MarcoCantini.bsky.social (internal), and Catherine Berry (convener) from @uofglasgow.bsky.social @theglasgowcemi.bsky.social

Really excited to tell you about our paper just out in the journal Matrix Biology. @erinboland.bsky.social set out to investigate what the impact of basement membrane defects are on adult heart function/biology. www.sciencedirect.com/science/arti...

Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function

Collagen IV is a major constituent of basement membranes and mutations in the genes COL4A1 and COL4A2 present clinically as a variable, multi-system d…

sciencedirect.com

Great to see that our work on #viscoelastic #hydrogels for #cartilage #TissueEngineering was one of the most-read papers in Advanced Healthcare Materials @mattjwalker.bsky.social @delphe.bsky.social @manlio-tassieri.bsky.social Check it out here doi.org/10.1002/adhm... 🧪

🧪This is just a teaser. Stay tuned for more information coming soon! #6thISMB

⚠️ Paper Alert ⚠️ Are you thinking of starting co-cultures of Living Materials with mammalian cells? Then give our paper a read on how to find the best culture conditions for both! www.sciencedirect.com/science/arti... Turns out bacteria are pickier than mammalian cells 😄 #livingmaterials #science

A screening setup to streamline in vitro engineered living material cultures with the host

Engineered living materials (ELMs), which usually comprise bacteria, fungi, or animal cells entrapped in polymeric matrices, offer limitless possibili…

sciencedirect.com

Paper⚠️ Have you wondered how to assess cytocompatibility on #engineeredlivingmaterials? Because they are ever evolving, it's important to follow how time affects their compatibility with the host. Here we propose a workflow just for that. Check it out! www.sciencedirect.com/science/arti...

A practical workflow for cytocompatibility assessment of living therapeutic materials

Living Therapeutic Materials (LTMs) are a promising alternative to polymeric drug carriers for long term release of biotherapeutics. LTMs contain livi…

sciencedirect.com

🔔 The final version of our COBME paper on how #hydrogel platforms with tunable / dynamic #mechanics enhance our understanding of #cancer progression and #fibrosis is out! 🧪 🌺 Thank you @marcocantini.bsky.social @mattjwalker.bsky.social #tissueengineering 👇 www.sciencedirect.com/science/arti...

Beyond static models: Mechanically dynamic matrices reveal new insights into cancer and fibrosis progression

The dynamic mechanical nature of extracellular matrices (ECMs) is crucial for the mechanosensitive regulation of cell fate. This is evident in patholo…

sciencedirect.com

Marco Cantini@marcocantini.bsky.social · 2y ago

Happy to share our Current Opinion by @mattjwalker.bsky.social and @delphe.bsky.social🧪 We review how advances in dynamic #hydrogel based #mechanobiology platforms are critical to understand disease progression in cancer and fibrosis @elsevierconnect.bsky.social www.sciencedirect.com/science/arti...

🎁🧧🥗We had such a lovely CeMi #Christmas lunch! 🎅🥗🎄 Join our Centre @theglasgowcemi.bsky.social 💝 #mechanobiology #6thISMB

Happy to share our Current Opinion by @mattjwalker.bsky.social and @delphe.bsky.social🧪 We review how advances in dynamic #hydrogel based #mechanobiology platforms are critical to understand disease progression in cancer and fibrosis @elsevierconnect.bsky.social www.sciencedirect.com/science/arti...

On behalf of the organizing committee (pic below), I'm thrilled to announce the 6th ISMB, the 2026 International Society of #Mechanobiology Meeting in #Glasgow. See you all there! 🧪 #InternationalSocietyMechanobiology #6thISMB Pic: G. Ciccone, O. Dobre, D. Gourdon, B. Martinac, M. Vassalli

Interested in how #stemcells sense their environment? Check out our work showing how #ECMatrix viscosity regulates #mechanosensing and #differentiation 🧪 Led by @theglasgowcemi.bsky.social @uofglasgow.bsky.social in collaboration with IBEC @natureportfolio.bsky.social www.nature.com/articles/s41...

N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity - Nature Communications

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...

nature.com

A forum for all things related to the cellular microenvironment and its role in health and disease. Spread the voice and drop a message if you want to join! go.bsky.app/jhvVHF