Please share: we’re recruiting a postdoctoral fellow – applications open until September 15! To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies. my.corehr.com/pls/uoxrecru...

What is the most common type of mutations, causing cancer and genetic diseases? C to T mutations in CpGs: Signature 1. What is the best understood mutational signature? Signature 1. Or is it? An intro thread about a paper we published last year... 🧵1/ www.nature.com/articles/s41...

Human DNA polymerase ε is a source of C>T mutations at CpG dinucleotides - Nature Genetics

A new method called polymerase error rate sequencing (PER-seq) can measure the nucleotide misincorporation rate of DNA polymerases. DNA polymerase ε mutants produce an excess of CpG<TpG errors duri...

nature.com

We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations. cutt.cx/YUoB We look forward hearing from you! #epigenetics #jobs