Very exciting to see our work being highlighted by @thetransmitter.bsky.social! Thanks to Natalia Mesa, and as always thanks to our collaborators in the Jayaraman lab!… back to grinding away at reviewer experiments

Yvette Fisher@yvetteefisher.bsky.social · 4w ago

Thank you Natalia Mesa at the @thetransmitter.bsky.social for highlighting our labs preprint on synaptic mechanisms of head direction learning!! 🪰🧭 Work from @markplitt.bsky.social in my lab in collaboration with the Jayaraman lab! www.thetransmitter.org/learning-and...

My final paper from grad school is out! Thank you to @marisosa.bsky.social @ellasay.bsky.social and my co-first author Konstantin Kaganovsky! We show that reward and novelty coding in the hippocampus requires a specific membrane fusion protein implicated in activity-dependent AMPAR mobilization!

Lisa Giocomo@lgiocomo.bsky.social · 4mo ago

New paper! Congrats to @markplitt.bsky.social, Konstantin and team! The brain’s spatial map isn’t static but for hippocampus CA1 maps to change with experience, they need postsynaptic membrane fusion. A new link between synaptic machinery and flexible coding! www.sciencedirect.com/science/arti...

My main postdoc work is now published: www.nature.com/articles/s41...! We (myself, Isabel Low, Frances Cho, and @lgiocomo.bsky.social) discovered task-relevant remote representations in entorhinal cortex independent of CA1. #paperthread below! 1/13

I am incredibly excited and proud to share my first preprint from my postdoc! Thank you to all of the co-authors for all your hard work! Check out the paper for big insights into plasticity mechanisms in navigation circuits! And surprising motifs for inhibitory synaptic plasticity!

Yvette Fisher@yvetteefisher.bsky.social · 8mo ago

*First preprint from our lab* !!!!! How does the brain learn to anchor its internal sense of direction to the outside world? 🧭 led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman: “Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6... Thread ⬇️

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

A flexible hippocampal population code for experience relative to reward - Nature Neuroscience

Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

nature.com