It’s 2026 and Britains best hope of stopping the rise of fascism is a novelty political candidate dressed as a bin Whatever else this generation does, at least our history is not boring #Binface #BoatMcBoatface #Democracy

Count Binface reacts to 'hilarious' chance of becoming an actual MP

YouTube video by LBC

youtu.be

🐝 Animal #1073 🐁 I figured it out in 3 guesses! 🟨🟩🟩 🔥 5 | Avg. Guesses: 7.1 metazooa.com #metazooa

Metazooa

Become an evolutionary detective to find the Mystery Animal!

metazooa.com

Denies poor planning?😨 What was it then: A calculated move? A brilliant strategy? A cunning plan? I know some brilliant, dedicated clinicians @ Palmy North Hospital & there is soo much talent in HealthNZ / TeWhatuOra. I just wish the talent extended up to the government that thinks it’s leading us

'It is a challenge' - Health NZ denies poor planning led to lack of gastro doctors at Palmerston North Hospital

Health NZ says Palmerston North Hospital has not been left without any gastroenterologists because of poor planning on its part.

rnz.co.nz

We all know Oligarchs are bad 😡 But how about a trillionaire who appears on the side of a building looking and behaving like a Bond villain… And takers? Are we OK with this? 😬👍

I find #AI really irritating, in a sort of constantly tiresome way like having a stone in my shoe It’s like the Spice Girls. In 1996 everyone was going crazy for Wannabe. I thought they were crap, but had to live in a world where everyone loved them for a while Any tips for coping with this?

Sad to hear of the death of Professor Richard Scolyer. A true giant of the field of melanoma, and a brave advocate of cancer research and for those living with cancer www.theguardian.com/society/2026...

Richard Scolyer shares his ‘greatest lesson’ in open letter to Australians before his death

‘My intention is for this letter to be published upon my passing – as my final farewell,’ famed cancer researcher writes

theguardian.com

Latest update on #CROWN shows mPFS for lorlatinib still not reached at 7 years. Benefit across all subgroups including brain mets. This should push us to examine the paradigm: at what point does ‘incurable cancer’ become ‘chronic disease’? #ASCO26 #NSCLC #ALK #LCSM

Impressive improvement in PFS. Exciting option to bring targeted therapy forward into first line, delaying use of chemo. OS data still immature and rates of G≥3 tox high for Sunvoz, exceeding that of Chemo. Much to consider… #ASCO26 #LCSM

NEJM.org@nejm.org · 2mo ago

In NSCLC with 𝘌𝘎𝘍𝘙 exon 20 insertions, first-line sunvozertinib led to longer progression-free survival than chemotherapy. The most common adverse events of grade 3 or higher were elevated creatine kinase, diarrhea, and anemia. Full phase 3 WU-KONG28 trial results: https://nej.md/4fQWMwa #ASCO26

This news article gives a really clear lay-language summary of the pros and cons of #prostatecancer #screening. Well worth a read for blokes over 50 Yes there is a test. The test isn’t perfect. Risks outweigh the gains for most men who feel well and have no symptoms www.bbc.co.uk/news/article...

Prostate cancer screening only for "a few thousand" at risk men

Only men with a dangerous genetic variant and a family history of cancer should be offered screening, say UK advisors.

bbc.co.uk

UK National Screening Committee report on #ProstateCancer balanced + evidence based No test is perfect, screening can do more harm than good Appreciate some are disappointed. The way forward is to develop better screening tests view-health-screening-recommendations.service.gov.uk/prostate-can...

Prostate cancer - UK National Screening Committee (UK NSC) - GOV.UK

view-health-screening-recommendations.service.gov.uk

It’s #ASCO26 week! @ascocancer.bsky.social Top picks that I’m excited about are: 1) HARMONi-6 OS results of Ivonescimab + chemo vs tislelizumab+chemo I’m 1° setting for advanced squamous NSCLC. Ivo data soo far has been promising, this could be a new SoC🫁 #lcsm #NSCLC #oncsky

It’s #ASCO26 week! 🦀 ASCO, run by @ascocancer.bsky.social is the biggest scientific conference in the world. Sometimes described as the Olympics of Oncology or WorldCup of Cancer Research. Much of the most impactful research of the year will be presented. My top picks and ones to watch to follow…

I’m a dual citizen 🇬🇧&🇳🇿. I have both passports - seems obvious and sensible to me UK rules changing. @theguardian.com mentions x4 in article below that ‘certificate of entitlement’ costs £589 They don’t mention the far cheaper option of renewing/getting a full UK passport for £94.50

Dual nationals to be denied entry to UK from 25 February unless they have British passport

New border controls require ‘certificate of entitlement’ to attach to second nationality passport that costs £589

theguardian.com

I grew up in Dumfries & Galloway, highly reccommend it. Would be a great area to move to with a family. Rural and outdoor living but also under 90mins drive to Glasgow/ 2hours to Edinburgh

cally pigeon@gasbagheera.bsky.social · 7mo ago

Hola folks - are you CCT’ing? Do you fancy a varied job in Scotland’s best kept secret - Dumfries & Galloway? The department and facilities are excellent, the hills are nearby. Happy to answer questions and queries. And feel free to RT folks! apply.jobs.scot.nhs.uk/Job/JobDetai...

Happy New Year! I think this year is going to be a good year

Got a sandwich today from Britains iconic bakery chain: Greggs lady “did you ken there’s a Greggs Diet now?” Me “oh aye? Does it work?” Greggs lady “I’d have tae say No. Not if you’re wanting tae lose weight” #greggs #bakery #Diet #weightloss #healthyeating #newyear #resolution #scotland

‘Specialist of your choice’ is an odd criteria for hospital healthcare. People often don’t know which exactly which spcialist they need. A well run public system can triage anyone to the right place equitably Do you expect to pick your own pilot when you fly? (To be fair, @mcuban.bsky.social might)

Mark Cuban@mcuban.bsky.social · 7mo ago

The UK is very different from Medicare. In Medicare you can mostly go to a specialist of your choice. Not in the UK This is how most UHC works. Will Americans be ok with this change to Medicare ? Referrals for specialist care - NHS share.google/X84C9oCy1rE1...

Are you rich & don’t like paying taxes? Buy land!! Keir Starmer has decided to only charge inheritance tax to agricultural landowners on estates over £2.5million However if your only asset is a family home, you start paying inheritance tax at £325,000 What’s the point of this labour government?

Government waters down farm inheritance tax plan

The government has now said it will lift the intended threshold from £1m to £2.5m.

bbc.com

It comes to my attention that Americans don’t use the word ‘tortoise’ & call #tortoises (ie the slow moving guys who sleep all winter) #turtles (ie the ocean dwelling dudes) and sometimes call them ‘land turtles’ 🐢 All tortoises are turtles. But not all turtles are tortoises. Tortoises are real

Remember to get your winter vaccine folks - it’s literally a potion that gives you more hit points.

BK. Titanji@boghuma.bsky.social · 8mo ago

I am currently on ID consult service. I saw my first severe case of post influenza staphylococcal pneumonia of the season today - very sick patient admitted to the ICU. Every patient I have seen so far admitted with influenza this week is unvaccinated. The vaccines keep you out of hospital! Get 💉💉💉

In the long term a world with good, caring, benevolent AI will generate domesticated people and a comfortable stagnant era without innovation A world with antagonistic AI will generate inequality and injustice and strife and response and progress to the next thing beyond AI

Senator Bernie Sanders@sanders.senate.gov · 8mo ago

Yes. We have to worry about AI and robotics. Some questions:

Do other men have this problem? Sometimes I wear a suit that I think looks decent, and then realise I look like a mafia boss from the 1930s #fashionformen #strongmidsection #mob

Costco has nicely laid out produce & most folks go knowing what food they need for the week Health insurance is a deliberately confusing marketplace, and most people can’t be reasonably expected to know what they need Universal healthcare is the answer to this in every other wealthy country

Dr. Zachary Rubin@rubinallergy.bsky.social · 9mo ago

Encouraging people to “be entrepreneurs” and negotiate their own health insurance with a multi-billion-dollar for-profit industry is like telling someone to take their Costco membership fee and go negotiate directly with food manufacturers.

$1Trillion is enough wealth for a million people to each become a millionaire It’s enough for 10million people to buy a small apartment and live in it It’s enough for 20million people to get a university education Nobody benefits from this much concentration of wealth Malignant capitalism

Elon Musk's $1tn pay deal approved by Tesla shareholders

The richest man in the world will get hundreds of millions of new shares if he hits his targets.

bbc.com

Happy Monday all, it’s Day4 of #ESMO25 My hot picks for today: ✅Updated data on #SWOG1801 & #NADINA ✅#SafeStopTrial (early discontinuation of CPI in CR/PR) ✅#STAMP (adj pembro in Merkel Cell) ✅Phase1 #IMA203 for 👁️Uveal Melanoma in Presidential session @oncoalert.bsky.social @myesmo.bsky.social

#HARMONi-6 & #OptiTROP-Lung04 both large phase-3 RCT in a china🇨🇳 only population. Both given Presidentials #ESMO25 Discussants commented re confirmatory trials in worldwide setting Is this necessary in 2025? Why don’t we consistently raise this question to EU/US trials?🇪🇺🇺🇸 #oncology #LCSM #oncsky

#OptiTROP-Lung04 🫁Sac-TMT (Trop2 ADC) vs Pt doublet in EGFR mutant #NSCLC 2nd line after targeted therapy mPFS 8.3 vs 4.3months mOS Not Reached vs 17.4months No ILD/pneumonitis. G3 Tox similar in both arms Exciting option, in a challenging setting #ESMO25 @oncoalert.bsky.social #LCSM

#HARMOMi-6 🫁Compared Ivonescimab (PD-1 + VEGF bispecific) vs Tizlelizumab (PD1) in combo ŵ Chemo in 1st line setting for squamous #NSCLC mPFS = 11.1 vs 6.9 months Benefit preserved across subgroups including PD-L1<1% OSdata awaited… No increase in tox This data is exciting #ESMO25 @OncoAlert

#ESMO25 Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine Translational work showing mechanism of increased INF-alpha leading to immune priming Phase III in development… @oncoalert.bsky.social

Good Morning Berlin! it’s day 3 of #ESMO25 My top picks today are: 🫁 HARMONi6 - Ivonescimab vs PD1 1st line in #NSCLC 🫁OptiTROP-Lung04 - sac-TMT in EGFR mutant NSCLC post TKI 🩻DREAM3R - Durva+CT 1st line in #Mesothelioma 🏌️ENZARAD (ANZUP 1303) - ADT + RT #LCSM @oncoalert.bsky.social