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Mat Upton

@matupton.bsky.social

Microbiology, antibiotic discovery, academic & chief scientific officer.

4 Posts60 Follower43 Folgt
Mat Upton@matupton.bsky.social · 3mo ago

Latest paper ( @jac-amr.bsky.social ) on in vivo activity of the lead compound at Amprologix - as effective as standard of care. Epidermicin NI01 demonstrates potent in vivo activity in a murine model of methicillin-resistant Staphylococcus aureus skin infection academic.oup.com/jacamr/artic...

Epidermicin NI01 demonstrates potent in vivo activity in a murine model of methicillin-resistant Staphylococcus aureus skin infection

AbstractObjectives. In the UK, over 16% of antibiotic prescriptions are for skin infections. New approaches are required to treat and prevent such infectio

academic.oup.com

Amprologix@amprologix.bsky.social · last yr.

Epidermicin NI01, has been featured in EMJ Reviews following a presentation by CSO @matupton.bsky.social at @escmid.bsky.social Global 2025. The data highlights efficacy in MRSA wound infections, and low risk of triggering allergic reactions - a promising step forward in the fight against AMR.

Epidermicin NI01, a First-in-Class Peptide Antibiotic Candidate, Has Potent Efficacy in a Robust MRSA Wound Infection Model and Low Allergic Reaction Liabilities

Over 10% of antibiotic prescriptions are for skin infections.1,2 New therapeutic approaches are required, and new modalities may be...

emjreviews.com

Mat Upton@matupton.bsky.social · last yr.

Genomics & phenotype of 3 Cupriavidus strains from cystic fibrosis lung - great team with PhD student Sean Kelly, @vickyb-micro.bsky.social @kmudz.bsky.social & clinical collaborators. High quality genomes, MDR to CF drugs, susceptible to pip/tazo & cefotax academic.oup.com/jambio/artic...

Genomic insights and phenotypic characterization of three multidrug resistant Cupriavidus strains from the cystic fibrosis lung

AbstractAims. We aimed to investigate phenotypic and genomic traits of three Cupriavidus spp. isolates recovered from people with cystic fibrosis (PWCF). T

academic.oup.com

Mat Upton@matupton.bsky.social · last yr.

Come & join us in stunning Plymouth & help develop vaccines for use in agriculture to reduce #AntimicrobialResistance. 1 week to closing date. Starts 1st June for 12 months. www.jobs.ac.uk/job/DMG178/p...

Post Doctoral Research Fellow in Microbial Genomics at University of Plymouth

An academic position as a Post Doctoral Research Fellow in Microbial Genomics is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.

jobs.ac.uk