Melike Dönertaş
@mdonertas.bsky.social
#aging #bioinformatics #microbiome #rstats Group Leader & Faculty @METU-Informatics Institute | Computational Biology & Ageing @iscb & @ekoevoder member https://donertas-group.github.io/
Super happy to share that I closed the loop and returned where my journey started.. This time as a faculty at METU Informatics Institute. Thanks so much to everyone who supported my journey so far! Looking forward to continue our collaborations & starting new ones 💪🤩
excited to share our new review on robust microbiome–aging research - with some personal context on why we wrote it 👇 (1/10) febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
The gut microbiome changes with age and associates with age-related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requ....
febs.onlinelibrary.wiley.com
Our group has a new home on the web that does the work justice ✨ donertas-group.github.io Huge thanks to Prasoon for building it 🙏
Dönertas Group
Dönertas Group Website
donertas-group.github.io
Check out our new review on evolutionary genetics of ageing 🔥 rdcu.be/fh3VU @natrevgenet.nature.com @leibnizfli.bsky.social @ihaucl.bsky.social
Every time a journal makes me convert my .csv/.tsv supplementary files to Excel, a little piece of open science dies🥀 RIP reproducibility, my floating-point precision, and at least a dozen genes that are now formatted as dates.
Aging killifish show systemic inflammation and accumulating DNA damage in progenitor-like immune cells, offering a window into the evolutionarily conserved mechanisms of vertebrate immune aging. Great work from Gabriele, @mdonertas.bsky.social, and the whole team. www.nature.com/articles/s43...
Spontaneous aging-associated inflammation and genome instability in the immune system of turquoise killifish - Nature Aging
Turquoise killifish are naturally short-lived vertebrates that serve as a model system for aging. The authors show that killifish exhibit age-related transformation in the immune system, which rapidly...
nature.com
maybe now i can finally learn german - just built a telegram bot that pings me every 30min with random prompts to make me speak, tracks my personal errors & resurfaces them until i get it right 3x, has conversation memory, 16k SRS cards & voice support. Hallo, Welt 🇩🇪 👋
Nature Aging @nataging.nature.com turns 5 and asked ~50 researchers to reflect on the field. I am honored to contribute alongside colleagues whose work has shaped how I think about #aging science. Past, present and future perspectives on the science of aging www.nature.com/articles/s43...
Super happy to share the first research paper from our group! 🎉 We asked if the transcriptome helps us predict SA-β-gal status using Moiseeva mouse senescence atlas data 🐭 Spoiler: single gene markers don't perform well, ML can make a difference 👇 doi.org/10.64898/202...
Integrative transcriptomic identification of cellular senescence beyond marker limitations
Cellular senescence lacks a universal marker and varies across cell types, tissues, and stressors, complicating identification. Using SPiDER SA-β-gal labeled single-cell RNA-seq from regenerating mous...
doi.org
Happy to share that this is now out in Microbial Ecology 🥳 Huge thanks to the whole team, especially @sultanova.bsky.social 🙌 link.springer.com/article/10.1... @leibnizfli.bsky.social @uniofeastanglia.bsky.social
Age-Dependent Gut Microbiota Dynamics and Their Association with Male Life-History Traits in Drosophila melanogaster - Microbial Ecology
Growing evidence suggests that the gut microbiota is closely intertwined with life-history evolution in a wide range of species, including well-studied model organisms like Drosophila melanogaster. Al...
link.springer.com
Melike Dönertaş@mdonertas.bsky.social · last yr.Super happy to share our new preprint with Zahida Sultanova and an amazing team! We explored how age-related changes in gut microbiota associate with life history traits - lifespan, reproduction, and performance - in male Drosophila melanogaster. www.biorxiv.org/content/10.1...
Join EMBL's Interdisciplinary Postdoc Programme! 3 years funding, self-designed interdisciplinary project co-led between EMBL PI and PI in one of EMBL's actual, prospect or associate member states. In particular: AI&Theory, use mathem. models, physics principles and AI www.embl.org/about/info/p...
EIPOD-LinC Fellowship Programme – Postdoctoral Programme
embl.org
I hereby declare email bankruptcy. If you’ve written to me in the past months and haven’t heard back — it’s not you, it’s the inbox. I recently discovered that hundreds of messages had been flagged as spam and never reached me. 👇
#AMC2025 is almost here (Oct 28–29, Jena) and we’ve opened a few more seats! If you work on host-microbiome interactions, aging, or age-related diseases, bring a poster and join this amazing crowd! amc25.leibniz-fli.de/registration/ ✨ Highlights 👇 🧵 (1/4)
We are in Liverpool for the #ISMBECCB2025! Tayyaba Alvi, Mark Olenik and I will be delivering a tutorial on Mendelian Randomization on the first day of the conference. (1/3)
Happy to share our new study from my PhD on the spread of farming across Anatolia and into the Aegean and then into Europe. @compevohumang.bsky.social www.science.org/doi/10.1126/... 👇🏽
Out-of-Anatolia: Cultural and genetic interactions during the Neolithic expansion in the Aegean
West Anatolia has been a crucial yet elusive element in the Neolithic expansion from the Fertile Crescent to Europe. In this work, we describe the changing genetic and cultural landscapes of early Hol...
science.org
📢 REMINDER ‼️ AMC - Abstract submission deadline: June 30, 2025 The Aging and Microbiome Conference 2025 #AMC2025 will take place from October 28-29, 2025 in #Jena. Join us for the latest developments and exciting discussions on #microbiome & #aging. 📅 amc25.leibniz-fli.de/registration/
📢 Update! The abstract submission deadline for the #AMC2025 Aging and Microbiome Conference has been extended to June 30, 2025! 🔗 amc25.leibniz-fli.de 📌 Jena, Germany 📆 Oct 28-29, 2025
I'm attending #ISMBECCB2025 in Liverpool, United Kingdom from July 20-24. Who else is going? Register here and don't miss it! invt.io/1bxb8kd9bqu
I'm participating the ISMB/ECCB 2025 conference, join me!
Register now
invt.io
📢 Update! The abstract submission deadline for the #AMC2025 Aging and Microbiome Conference has been extended to June 30, 2025! 🔗 amc25.leibniz-fli.de 📌 Jena, Germany 📆 Oct 28-29, 2025
A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging www.nature.com/articles/s43...
A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging
Fuentealba and colleagues build and validate a DNA methylation clock of intrinsic capacity (IC) to bridge resource-intensive clinical assessments of IC with molecular readouts of aging, highlighting…
nature.com
Super happy to share our new preprint with Zahida Sultanova and an amazing team! We explored how age-related changes in gut microbiota associate with life history traits - lifespan, reproduction, and performance - in male Drosophila melanogaster. www.biorxiv.org/content/10.1...
Age-dependent gut microbiota dynamics and their association with male fitness traits in Drosophila melanogaster
Growing evidence suggests that the gut microbiota plays a key role in shaping life history in a wide range of species, including well-studied model organisms like Drosophila melanogaster. Although rec...
biorxiv.org
🚨 Aging and Microbiome Conference 2025 📌 Jena, Germany 📆 October 28-29, 2025 ⏰ Abstract submission deadline: 31.05.2025 ℹ️ amc25.leibniz-fli.de
First evidence of possible language-like communication in dolphins phys.org/news/2025-05...
First evidence of possible language-like communication in dolphins
Researchers at the Woods Hole Oceanographic Institution (WHOI) and partner institutions, including the Brookfield Zoo Chicago's Sarasota Dolphin Research Program (SDRP), are the winners of the…
phys.org
🚨 Aging and Microbiome Conference 2025 📌 Jena, Germany 📆 October 28-29, 2025 ⏰ Abstract submission deadline: 31.05.2025 ℹ️ amc25.leibniz-fli.de
Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool - Nature Communications www.nature.com/articles/s41...
Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool - Nature Communications
Haematopoietic stem cells (HSC) are responsible for blood cell generation and reside in the bone marrow. Here, the authors show that macrophages in the bone marrow originate from embryonic or adult…
nature.com
Happy to have contributed a chapter to the Encyclopedia of Bioinformatics and Computational Biology (2nd ed.) with Mark Olenik. We explore ML & Omics for predicting health and chronic disease www.sciencedirect.com/science/arti...
Machine Learning and Omic Data for Prediction of Health and Chronic Diseases
Machine learning (ML) combined with diverse omic datasets offers transformative potential for predicting health outcomes and chronic diseases. By leve…
sciencedirect.com
📢 Super excited to announce the Aging and Microbiome Conference 2025 #AMC2025 in Jena, Germany! Join us on October 28–29 for the latest developments and exciting discussions on #microbiome & #aging 📅 Registrations open March 28 🌐 amc25.leibniz-fli.de Please help us spread the word!
Nature publishing a piece on unpaid academic labor is the best joke I’ve read in a while. www.nature.com/articles/d41...
I spent two years organizing an international conference. How do I get compensated for my work?
It can be hard to say no to service requests in academia. Nature’s Careers team sought advice on how to ensure researchers don’t get stuck doing unpaid labour.
nature.com
➡ New GPU modules for the laboratory of Dr. Handan Melike Dönertaş With support from Carl-Zeiss-Stiftung, the Dönertas Lab at the @leibnizfli.bsky.social acquired new GPU modules to accelerate large-scale multi-omics data analysis and the development of machine learning and deep learning models.
