Uncovering the initial response: Intra-mitochondrial surveillance activates the UPRmt: Molecular Cell www.cell.com/molecular-ce...

Uncovering the initial response: Intra-mitochondrial surveillance activates the UPRmt

Taskin, Shankar, Peselj, et al. demonstrate that mitochondria possess an intrinsic surveillance system that senses mild oxidative stress and activates the UPRmt before damage signals reach the cytosol...

cell.com

Congratulations to our SFB 1381 PIs Claudine Kraft and Carola Hunte and their teams - great story on the link between the mitochondrial fission and autophagy machinery!

Claudine Kraft's Lab @kraftlabfr.bsky.social · 4mo ago

🚨 Paper Alert! In this new work published in @jcellsci.bsky.social we shift our focus on MTFR1L and the feedback loop linking mitochondrial fission, mitophagy and apoptosis. MTFR1L emerges as a critical coordinator of the fission and autophagy machinery. 🔗Find the paper here: doi.org/10.1242/jcs....

👋 It’s been four weeks since our fantastic SFB 131 symposium, which featured an amazing line up and great participants. 🎬 Watch the video to relive the vibe!

Getting ready for our upcoming symposium! We are excited to welcome our international speakers and all other participants to Freiburg next week for what promises to be an unforgettable SFB 1381 Symposium.

The Meisinger Lab wishes all mito friends and colleagues a Merry Christmas and a peaceful 2026!

Interested in how to clarify a fundamental clash in mitochondrial signalling ? Check it out at www.nature.com/articles/s41...

DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring - Nature Communications

Most mitochondrial proteins are imported from the cytosol via the TOM complex. Here, Marada et al. identify DYRK1A as a surveillance kinase that synchronizes the different import routes to shape the o...

nature.com