A key takeaway is that derivatization can provide both enhanced analytical detection and characteristic fragmentation patterns for systematic metabolite discovery—an exciting direction for comprehensive exposure and metabolomics research. pubs.acs.org/esthag/artic... #Exposomics #Metabolomics #NTA
Mehedi Hasan Nafis
@mh-nafis.bsky.social
PhD researcher in environmental analytical chemistry. Chemical exposome, metabolome & LC-HRMS. I share papers I read, method explainers, and honest notes from PhD life.
🔬 A promising direction for metabolomics, exposomics, and environmental chemical analysis. uMRM enables the creation of quantitative MRM methods directly from discovery experiments. #MassSpectrometry #LC-MS #metabolomics #exposomics #uMRM
Untargeted Multiple Reaction Monitoring
Abstract. Multiple reaction monitoring (MRM) enables robust and sensitive quantification but traditionally requires predefined precursor–fragment transitio
pubs.acs.org
Over 350,000 chemicals and mixtures are registered for production and use worldwide. We can routinely measure only a small fraction. That gap — between what we're exposed to and what we can detect — is basically why the exposome exists as a field. pubs.acs.org/esthag/artic...
Toward a Global Understanding of Chemical Pollution: A First Comprehensive Analysis of National and Regional Chemical Inventories
Abstract. Chemicals, while bringing benefits to society, may be released during their lifecycles and possibly cause harm to humans and ecosystems. Chemical
pubs.acs.org