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Michelle Lupton

@michelleklupton.bsky.social

Head of the Neurogenetics and Dementia group at QIMR Berghofer @qimrb.bsky.social

7 Posts39 Follower85 Folgt
Psychiatric Genomics Consortium (PGC)@pgcgenetics.bsky.social · 4mo ago

📄 Now published in Nature Human Behaviour, read the paper here👇 www.nature.com/articles/s41...

Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry - Nature Human Behaviour

Analysing generalized anxiety symptoms as a quantitative trait rather than a clinical diagnosis, Skelton, Mitchell and colleagues report a genome-wide meta-analysis of 693,869 individuals identifying ...

nature.com

Michelle Lupton@michelleklupton.bsky.social · 8mo ago

Proud to have contributed to the largest GWAS of anxiety, now published in Nature Genetics www.nature.com/articles/s41... #PISA_DementiaStudy #NGDgroup

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling - Nature Genetics

Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism...

nature.com

Michelle Lupton@michelleklupton.bsky.social · 11mo ago

Check out the free HEAL Network @healenviron.bsky.social online conference starting today. We have three posters on our research into bushfire smoke exposure and brain health from Peta Cridland, Emily Vivian and Jodi Thomas #PISA_DementiaStudy #NGDgroup

The HEAL Network@healenviron.bsky.social · 12mo ago

🚨 Look at this fantastic line-up of keynote speakers for #HEAL2025 🎤 Join us & hear from leading researchers, First Nations leaders, policymakers & community advocates share insights on the urgent #health, #climate, & #environmental challenges facing us. healnetwork.vfairs.com/en/

Michelle Lupton@michelleklupton.bsky.social · last yr.

Our newest preprint is now available, using Mendelian randomisation to investigate the causal relationship between Frailty and Alzheimer's disease. www.medrxiv.org/content/10.1... Awesome work from our visiting PhD student Jonny Flint #NGDgroup

Domains of Frailty as Early Risk Factors for Alzheimer Dementia - Genetic and Causal Evidence

Background Alzheimer’s dementia (AD) is a leading cause of disability and dependency in older adults. Frailty is a phenotypic risk factor for AD, but its causal role remains unclear - partly due to re...

medrxiv.org

Michelle Lupton@michelleklupton.bsky.social · last yr.

If you are heading to the ADRF conference in Perth next week, come along to our special research session for the DEMON Network on "The convergence of traditional and digital biomarkers: A new era for Alzheimer’s disease diagnostics?"

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Michelle Lupton@michelleklupton.bsky.social · last yr.

Proud to have contributed data to the largest GWAS of osteoarthritis, highlighting disease pathways and potential drug targets #PISA_DementiaStudy #NGDgroup rdcu.be/ehycr

Translational genomics of osteoarthritis in 1,962,069 individuals

Nature - A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of...

rdcu.be