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Micklefield Lab

@micklefield-lab.bsky.social

Solvitur ambulando - Biosynthesis; pathway engineering; enzyme discovery-structure-mechanism; biocatalysis & nucleic acids. Imperial College London - Molecular Sciences Research Hub

3 Posts203 Follower927 Folgt
Micklefield Lab@micklefield-lab.bsky.social · last wk.

Our latest article in Nature (@nature.com) reports the discovery of pathways to new polyene antifungals that outperform current clinical drugs and act via a different mechanism. Combating #AMR @imperialcollegeldn.bsky.social www.nature.com/articles/s41...

Enzymatic glycosylation and amidation reshapes polyene bioactivity - Nature

Pathways to previously undescribed polyenes, including unusual enzymes that introduce more sugars onto polyene scaffolds, are discovered, and their accessibility through clean and efficient fermentati...

nature.com

@eu-health.bsky.social · 6d ago

Antifungal drugs breakthrough tackles drug-resistant infections https://www.europesays.com/health/18680/ Scientists from Imperial College London and The University of Manchester have developed a new generation of antifungal drugs…

Antifungal drugs breakthrough tackles drug-resistant infections - Health Europe

Scientists from Imperial College London and The University of Manchester have developed a new generation of antifungal drugs that could offer safer and more

europesays.com

Micklefield Lab@micklefield-lab.bsky.social · last wk.

Our latest article in Nature (@nature.com) reports the discovery of pathways to new polyene antifungals that outperform current clinical drugs and act via a different mechanism. Combating #AMR @imperialcollegeldn.bsky.social www.nature.com/articles/s41...

Enzymatic glycosylation and amidation reshapes polyene bioactivity - Nature

Pathways to previously undescribed polyenes, including unusual enzymes that introduce more sugars onto polyene scaffolds, are discovered, and their accessibility through clean and efficient fermentati...

nature.com

Imperial Chemistry@imperialchemistry.bsky.social · last wk.

🚨New research from the @micklefield-lab.bsky.social. The team have uncovered a new class of antifungal agents that are more effective and less toxic than existing treatments. Read the full story: www.imperial.ac.uk/news/article...

New antimicrobials to combat deadly drug-resistant pathogens

Researchers from Imperial College London and The University of Manchester have developed a new family of antifungal compounds that could lead to safe...

imperial.ac.uk