New White House plan for science and technology released yesterday www.whitehouse.gov/releases/202... 1/9
OSTP Director Releases Landmark Report and Recommendations for Renewing American Scientific Discovery
WASHINGTON, DC – Today, Assistant to the President and Director of the White House Office of Science and Technology Policy (OSTP) Michael Kratsios
whitehouse.gov
Russell Vought, Director of the OMB, has issued a set of proposed changes that would dramatically alter federal grant funding. However, we can each take action to prevent these from taking effect. Here's how, a 🧵 🧪 1/n www.science.org/content/arti...
White House seeks to tighten political oversight of grantmaking
Sweeping proposed rule, now open for comments, would also restrict foreign collaborations and remove federal funding for open-access fees
science.org
MARK YOU CALENDAR for our EMERGENCY SCIENCE MEETING June 2nd at 4pm ET. We will be giving an overview of the rule and assigning EVERY SCIENTIST IN AMERICA their marching orders. Register at the link in our bio, or go here: zurl.co/YVcXc #Science #StandUpForScience #OMB #SaveScience #Research
BREAKING: New proposed OMB regulation, applying to all federal grants, requiring grant reviews by senior political appointees and re-emphasizes that "peer review remains advisory and does not replace agency discretion". #standupforscience public-inspection.federalregister.gov/2026-10817.pdf
public-inspection.federalregister.gov
A day in the life of a growing hiPSC spheroid expressing endogenously mStayGold-tagged histone 3.3 for #FluorescenceFriday and the #Snouty aficionados. 28 hours (and >50,000 exposures) later and they are still going! Home-brewed volume projection.
@jeremymberg.bsky.social how come that there were ~7000 more NIH grant applications in 2025 compared to 23/24? Who wrote those? AI?
Good story from Vox on falling numbers of new and competitive renewal R01 grants. [Gift Link] www.vox.com/future-perfe... 1/5
The US slashed research for cancer, Alzheimer’s, mental health — and nearly everything else
Revealed in one chart.
vox.com
NIH has not updated the overall success rates pages drugmonkey.wordpress.com/2026/03/12/n...
NIH has not updated the overall success rates pages
The NIH finally updated the data underlying good ol’ Report 302 of the Databook to include FY2025, which ended 09/30/2025. This allows us to examine the fate of R01-Equivalent applications by…
drugmonkey.wordpress.com
A short Bluetorial on plots of NIH application success rates as a function of percentile. 1/20
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
Does anyone know of an anti mStayGold antibody that works for immunoblots / IP? Anyone tried the one from HUABIO (not even sure that’s a real company)? Thanks!
The hidden danger of Biorender (& the death of scientific illustration) A short thread 🧵
🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/
Meet Paul Maddox
Paul Maddox is a world-renowned cancer researcher, two-time entrepreneur, and native son of Western North Carolina–and now, a candidate for U.S. Congress. ....
maddoxforcongress.com
Playing around with how to represent volume in #Snouty light sheet data. Here is a dividing hiPSC with endogenously tagged histone in all three orthogonal projections. Bluer is further away. If anything, it distracts from politics.
'Innovation does not occur in a vacuum. It requires raw materials: the findings of basic research. We are currently burning through a stockpile of knowledge accumulated during a more enlightened era of public investment, while allocating insufficient resources for replenishing it.'
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
embopress.org
Some first raw (not deskewed) data of live human induced pluripotent stem cells from #Snouty now ready for some serious live imaging. Light sheet moving at a 38-degree angle through the cell layer; coverslip is on the bottom.
Finally having some time to play with ‘Snouty’ again. Thanks a million once more @tanner-fadero.bsky.social and @amsikking.bsky.social
Vaccine samples from the 1880s in Louis Pasteur’s laboratory in Arbois … Vaccines work!
Bluetorial: Non-Competitive Renewal (Continuation) Awards Normally, multiyear NIH grants are paid with awards each year, pending administratively reviewed progress reports. “NIH” has been slow in making these awards. This has led to $1.83 B being withheld from institutions through February 2025.
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
media.tenor.com
At the North Bay Science Discovery Day today in Santa Rosa
WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025
“The idea is that the public has the right to know who’s giving advice to the federal government and when they’re meeting,” said Jeremy Berg, a genetic scientist who has overseen NIH funding in the past. 1/3 [I am a genetic scientist in the sense that I have genes, but I am a biochemist]
New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n
Trump Administration Stalls Scientific Research Despite Court Ruling (Gift Article)
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
nytimes.com
Myths vs. Facts regarding federal cuts to f&a (indirect) costs on NIH grants... 🧪 medsky 🛟😷 sociology idsky ucop.edu/communicatio...
ucop.edu
I can’t believe this is happening: grants awarded by the NIH cannot be funded for the foreseeable future because of a hold on submissions to the Federal Register, where such public notices about upcoming meetings are required by law to be posted www.thetransmitter.org/funding/fede...
Federal Register hold makes ‘end run’ around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
thetransmitter.org
"At NIH, offices involved in reviewing and administering grants to researchers outside the agency, such as at universities and medical centers, were hit hard, one staffer with knowledge of the situation said." www.npr.org/sections/sho...
Health agencies lose staff members in key areas as Trump firings set in
As the dust settles from the first wave of firings at health agencies, here's how many people got cut and the impact of the roles that were lost.
npr.org
