Mike Russo

@mikerusso.bsky.social

Peds ID in Philly. Full time clinician. Transplant, NTM, tick-borne infections, and antibiotic allergies. Pro oral antibiotics and short durations Anti cefdinir (He/him) #IDSky

This is why clinical trials are important. Unfortunately tecovirimat did not improve resolution of clade IIb mpox compared to placebo. There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.

Liz Highleyman@lizhighleyman.bsky.social · 2y ago

Turns out the antiviral TPOXX (tecovirimat) doesn't work for mild/moderate Clade II #mpox ( #monkeypox) either, as previously shown for Clade I. Many treated people reported improvement, but symptoms typically resolve anyway -- that's why we need controlled trials. www.niaid.nih.gov/news-events/...