Mike Russo
@mikerusso.bsky.social
Peds ID in Philly. Full time clinician. Transplant, NTM, tick-borne infections, and antibiotic allergies. Pro oral antibiotics and short durations Anti cefdinir (He/him) #IDSky
This is why clinical trials are important. Unfortunately tecovirimat did not improve resolution of clade IIb mpox compared to placebo. There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.
Turns out the antiviral TPOXX (tecovirimat) doesn't work for mild/moderate Clade II #mpox ( #monkeypox) either, as previously shown for Clade I. Many treated people reported improvement, but symptoms typically resolve anyway -- that's why we need controlled trials. www.niaid.nih.gov/news-events/...
The dramatic changes this has brought have been humbling to witness. Hope for improved access worldwide and modulators for those with rarer mutations next.
CFTR gene cloned in 1989. Combined CFTR modulators elexacaftor-tezacaftor-ivacaftor (ETI) approved in 2019 --> "The introduction of ETI has dramatically reduced the need for lung transplants among people with CF, reflecting significant improvements in lung function and disease management."🧪⚕️
1/8 Our report of the first confirmed cases of transplant derived Bartonella quintana infection and the public health investigation surrounding them has been published! #medsky #idsky #publichealthsky #txid wwwnc.cdc.gov/eid/article/...
<em>Bartonella quintana</em> Infection in Kidney Transplant Recipients from Donor Experiencing Homelessness, United States, 2022
<em>B. quintana</em> Infection from Kidney Donor
wwwnc.cdc.gov
“Measles, stand back and stand by,” sums all of *this* up pretty well…
this column is what comes out when you smash your head repeatedly into the keyboard in a fit of rage wapo.st/3Z6fMhu
We can pray he won’t get confirmed. But if he does, doctors who’s normalized RFK Jr. own the next 4 years. So do the doctors who normalized these cranks and charlatans. My latest for SBM. sciencebasedmedicine.org/ownit/
If You Sanewashed RFK Jr., Or If You Sanewashed Doctors Who Did, You Own the Next 4 Years | Science-Based Medicine
When RFK Jr. does to the U.S. what he did to Samoa, doctors will say they are horrified, that they love vaccines, blah blah blah. But it will be too late.
sciencebasedmedicine.org
Summoning the rest of PedsID to Bluesky: Cefdinir, cefdinir, cefdinir! #idsky #medsky #cefdiniristrash