We're hiring at the Assistant #Professor level in #Medicinal / #Biological #Chemistry and Chemical Biology. Please share with anyone you think might be interested. jobs.utoronto.ca/job/Mississa...

Just out....ahead of print...our review article in #MBoC on how mechanical effects shape #bacterial dynamics and #ecology in dense and confined environments www.molbiolcell.org/doi/10.1091/...

Bacterial ecology in confined and spatially structured in vitro habitats | Molecular Biology of the Cell

Bacteria commonly coexist within communities where they compete for limited space and resources. These communities play an essential role in supporting a diversity of critical ecosystems from regulati...

molbiolcell.org

Another successful collaboration with the Beharry Lab on light activated #antimicrobials chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1...

The Biophysical Society of Canada is pleased to announce that Dr. Sarah Rauscher @sarahrauscher.bsky.social is the recipient of the 2026 Early Career Investigator Award. Congratulations!!

#INSPIRE2026 is now open for registration. Spend 2-weeks getting hands on experience in #QuantitativeBiology and #ResearchTranslation @utm.utoronto.ca www.utm.utoronto.ca/dean/inspire

INSPIRE | Office of the Vice-Principal Academic and Dean

U of T's Interdisciplinary Science Program in Research & Entrepreneurship Discover the Quantitative BiosciencesJune 15–26, 2026Join a two‑week immersive research experience where you’ll explore unanswered biological questions inside state‑of‑the‑art laboratories.

utm.utoronto.ca

Just out…our recent preprint on how she shapes of #bacteria can affect the stability of the #microbial communities they form www.biorxiv.org/content/10.6...

Learn more about #INSPIRE, a program we developed at the interface of #biophysics, drug development, #innovation and #entrepreneurship www.youtube.com/watch?v=EmwL...

2025 INSPIRE Scholars Program

YouTube video by Office of VP Research & Innovation at UTM

youtube.com

At long last, are newest article on "Enhancing the applied force and range of axial optical tweezers” is out. #singlemolecule #biophysics www.cell.com/biophysrepor...

Enhancing the applied force and range of axial optical tweezers

Axial optical tweezers provide a natural geometry for performing biomechanical assays, such as rupture force measurements of protein binding. Axial traps, however, are typically weaker than their late...

cell.com

Our experimental lab w/ the Hilfinger lab @uoft.bsky.social are jointly looking to hire a #postdoc in experimental biological #physics. Exploring noise and dynamics within single-cells and bacterial populations. Please share with anyone you think might be interested.

Here’s a great opportunity if you know of anyone looking for a postdoc.

@davidasivak.bsky.social · last yr.

Postdoc opportunity! Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment. Details: www.sfu.ca/physics/siva...

This is based on our publication in #BioinformaticsAdvances, but is much much faster, does all the preprocessing for you, and has a nice GUI. academic.oup.com/bioinformati...

An expectation–maximization approach to quantifying protein stoichiometry with single-molecule imaging

AbstractMotivation. Single-molecule localization microscopy (SMLM) is a super-resolution technique capable of rendering nanometer scale images of cellular

academic.oup.com

If anyone is interested, we’ve developed a nice GUI in Python for molecular counting with #SMLM. Just give it a localization file and it will estimate the monomer/dimer fraction. github.com/thericshi/pr...

GitHub - thericshi/protein-stoichiometry-quantifier

Contribute to thericshi/protein-stoichiometry-quantifier development by creating an account on GitHub.

github.com

A big shout out to everyone who’s marching at today’s #standupforscience events.

Another successful collaboration with the Beharry lab on #antimicrobial photodynamic therapy. This just out in @rscmedchem.rsc.org: pubs.rsc.org/en/content/a...

Nitroreductase-activatable photosensitizers for selective antimicrobial photodynamic therapy

Antimicrobial photodynamic therapy (aPDT) utilizes light, oxygen and a photosensitizer (PS) to enact cell death via the production of reactive oxygen species (ROS). This mechanism of cell death, via o...

pubs.rsc.org

Sometimes reading Hamming makes me sad, because I recognize myself in this quote.

Here’s an event I would highly recommend. Just around the corner if you’re in the GTA.

actionnetwork.org/petitions/de...

Dear Future Premier, science needs to be a priority.

I just signed a letter to put science and evidence-informed decision-making at the heart of our provincial elections!🗳️🔬 In the upcoming elections in Ontario, it's crucial that our future premiers pr...

actionnetwork.org

Lots of #imaging and #microscopy workshops coming up in Canada. Just thought I would share. Thanks @bioimagingna.bsky.social and #CanadaBioimaging

Here’s a bit more information on #INSPIRE2024. Feel free to print out and post.

Registration for #INSPIRE2025 is open to all #Physics, #Chemistry, and #Biology undergraduates with an interest in Quantitative Biological and Translational Sciences. Work directly in labs @uoft.bsky.social @uoftmississauga.bsky.social while also learning about #innovation and #entrepreneurship.

Look what I just found in my mailbox. It’s nice to finally see this is print.

Pleased to see that #SpinUP made the news. Lot’s of innovative research translation efforts happening here @uoftmississauga.bsky.social @uoft.bsky.social www.theglobeandmail.com/business/art...

Why Canada excels at medical tech startups

The Globe and Mail offers the most authoritative news in Canada, featuring national and international news

theglobeandmail.com

Forget a clean room, we can do most of our larger feature #microfluidics on a resin based #3Dprinter. Here’s a PDMS mold for a serpentine mixer that you can even bake at 120C.

Finally starting to get this system working. While these movies might not look too impressive, they make me feel good. #microfluidics #biophysics

We’re looking to hire a theoretical #biological #physicist at either the Assistant or Associate professor level. The post closes soon, so please spread the word. #Toronto is a great place to live and work. jobs.utoronto.ca/job/Toronto-... jobs.utoronto.ca/job/Toronto-...

Congrats to Zhang and Tianyi on successfully pulling off their #PhDs! Now I need more students…so if you know of anyone...

And here’s a movie of one of our microchannel competition experiments. It shows how spontaneous ordering of the cells can lead to a quasi-stable, mixed bacterial community.

Oh, and finally, our side hustle is working with medicinal chemists to develop novel #antimicrobials. Here’s our latest effort with Andrew Beharry's lab chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Antimicrobial Efficacy of Photocaged β‐Lapachone in Bacillus subtilis Biofilms

Photocaged β-lapachone uncages effectively in B. subtilis biofilms using λ=420 nm light, causing catalase inhibition, leading to inhibition of growth. With antimicrobial resistance on the rise, an al....

chemistry-europe.onlinelibrary.wiley.com

And the other half of our time is spent developing single-molecule imaging, with a particular emphasis on counting molecules and defining the oligomerization state of membrane proteins (particularly #GPCRs).

We have also been developing ecological theories of bacterial competition within confined environments