Impressive experiments and - of course - beautiful imaging 😍

Christophe 🔬 Leterrier@christlet.bsky.social · 7mo ago

🚨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 🧵 1/9

Just look at those microtubules go! Happy to see our paper out in JCS ✨

Journal of Cell Science@jcellsci.bsky.social · 8mo ago

Malina Iwanski @mkiwanski.bsky.social, Lukas Kapitein and colleagues discover that stable microtubules reverse their polarity during neuronal development. journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish

Time to get signed up for the Symposium on Structural Proteomics! This time at @humantechnopole.bsky.social in Milan 6th-8th October Full speaker lineup announced. Thanks to @thermofishersci.bsky.social @brukercorporation.bsky.social, Affipro and MSVision for support Info ssp2025.squarespace.com

My main PhD paper is on bioRxiv! 🥳 We used motor-PAINT, expansion microscopy, and live-cell imaging of StableMARK to map out how the microtubule cytoskeleton reorganizes during neuronal development. www.biorxiv.org/content/10.1...

Polarity reversal of stable microtubules during neuronal development

Neurons critically depend on long-distance transport orchestrated by motor proteins walking over their highly asymmetric microtubule cytoskeleton. These microtubules are organized uniformly in axons w...

biorxiv.org

Advances in microscopy mean we can now do more than just observe biology—we can control it. But how far can we really push this in mammalian cells with all their (beautiful but annoying) heterogeneity? 🧪🔬(🧵)

And perfect timing to get newbie me all up-to-date 💫

samlacey.bsky.social@samlacey.bsky.social · 2y ago

Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps. www.nature.com/articles/s41...

Hi folks! Lots of things changed in my life recently (!) but mainly (1) I finished my PhD in the lab of Lukas Kapitein focusing on microtubule stability and orientation in neurons and (2) I moved to Milan to start my postdoc with Gaia Pigino on tubulin post-translational modifications in cilia.