Miguel Liezun
@mliezun.bsky.social
Head of Engineering at foundational.bio Personal Blog mliezun.com
Last blog post here about writing web services in the AI era and how AI changes the way we should think about software architecture. mliezun.com/2026/05/17/w...
Writing web services in the AI-era
AI is making rewrites cheap and vulnerabilities easier to find. The stack that survives will be layered, boring at the boundaries, and easy for agents to swap one piece at a time.
mliezun.com
I've joined foundational.bio FoundationalBio is building a self-driving lab, an AI-native, fully automated laboratory that replaces manual workflows to make life-science experimentation dramatically faster and more reliable. If you're interested in the future of science, let's connect. 🧬
Foundational Bio
Foundational Bio is building a self-driving lab: an AI-native, fully automated laboratory that replaces manual workflows to dramatically increase the speed and reliability of life-science experimentat...
foundational.bio
For ~15 months I ran the same prompt on LLMs: “Profile this Rust interpreter, optimize bottlenecks, iterate while tests pass.” It always failed. In Dec 2025 (Gemini 3 Pro + Cursor), it worked end-to-end. → profiler setup → safe refactors → continuous validation mliezun.com/2026/05/14/w...
What happened in december 2025?
Im quite late to the discussion, but everyone has been saying that they have not written code since december. What happened? The release of Gemini 3 Pro, GPT-5.1 and Claude Opus 4.5 was a game changer...
mliezun.com
Gencove just released developer access for Gencove Consumer 🎉 There is now a REST API, MCP server, and OAuth 2.0 support, so users can connect their genetic data to the tools they choose, and partners can build more easily with Gencove data. enterprise.gencove.com/blog/api-mcp...
Gencove Consumer: API, MCP, and OAuth for consumer genetics - Gencove
enterprise.gencove.com
Working really hard to make it possible for me to work from anywhere. Why would I sit at a desk when I could work while wandering around Paris? #sam #ai #opensource #agents
We just launched a new consumer genetic test that reports your health related to 9 PRS values. Also, by default we provide VCF access (no need to contact) support. This is sequencing based, not genotyped. Go look at our website! gencove.com
🐍 caddy-snake v0.4.0 is out! CGo is gone. Pure Python bridge, no C compiler needed. Flask: 3,782 req/s vs 1,592 (Gunicorn+Caddy) FastAPI: 5,730 req/s vs 3,537 (Uvicorn+Caddy) Plus standalone app binaries. github.com/mliezun/cadd...
Release v0.4.0 · mliezun/caddy-snake
🐍 caddy-snake v0.4.0 Highlights Pure Python implementation - CGo/C layer removed (#158) The entire WSGI/ASGI bridge has been rewritten from C (cgo) to pure Python, communicating with Go over light...
github.com
Looking forward to host the following Demo Day #Paris #TechCommunity #ParisTech
Biere Code@bierecode.bsky.social · 7mo agoWe're hosting a Mini Demo Day at Bière & Code Paris! 🍻 If you've been building something. We want to see real, running projects (no pitches!). 📅 Thursday, March 19 · 7:30 PM – 9:30 PM 📍 Chez Ernest, 75019 Paris 👉 www.bierecode.com/updates/bcb-... #Paris #TechCommunity #DemoDay #Builders
BCB Mini Demo Day is scheduled! Come show off what you're building to other builders on March 19. www.meetup.com/biere-code-b... #bcb #beer #code #ai #cloud #web #programming #builders #paris
Bière & Code & Beer Mini Demo Day!, Thu, Mar 19, 2026, 7:30 PM | Meetup
🇫🇷 BCB Mini Demo Day ! (english below) On invite notre communauté à venir partager les projets sur lesquels vous bossez. On se retrouve au Chez Ernest, un super resto/b
meetup.com
New post: Building Vercel-style custom domains in Django 🎯 TL;DR: How to let users connect their own domains to your Django app (with wildcard DNS, automatic SSL, and dynamic routing). Full guide here: mliezun.com/2026/02/11/v... #Django #Python #WebDevelopment
Vercel-like development setup for Django using Caddy
Get {branch}.dev.yourdomain.com previews for Django (or any WSGI app) with a single VM, Caddy, and rsync—no Kubernetes required.
mliezun.com
🇫🇷 Venez prendre une bière avec nous cette semaine au bar L'Intrépide. 🇬🇧 Join us for a beer this week at L'Intrépide Bar. www.meetup.com/biere-code-b...
#TechMeetup Bière & Code & Beer, Thu, Jan 15, 2026, 8:00 PM | Meetup
🇫🇷 Bière & Code & Beer La prochaine version est prête à être déployée ! L'Intrépide cette fois-ci. Malheureusement, Food Society est fermé définitivement. \-\-\- 🇬🇧 Bi
meetup.com
We’re looking for a few partners/sponsors aligned with builders: – cloud & infra – hardware / PCB – dev tools – research & innovation orgs Low-key event, real demos, engaged builders. DMs open if you want to get involved 🤝
Just joined Bluesky! Go check out our page and join our meetup if you're around Paris! bierecode.com
Capabilities of AI tools are still advancing rapidly, doubling the length of tasks AI can do every 7 months. But what's more striking is that for Software Engineering this is accelerating at a higher pace. mliezun.com/2025/12/22/w...
What's in the future?
mliezun.com
Join us for the final Bière & Code of 2025! When: Thursday, December 18 Where: The Bombardier, 2 Place Du Panthéon, Paris Come share a drink, talk about your latest coding adventures, and celebrate the end of the year with the community. www.bierecode.com/updates/end-...
Last Bière & Code of 2025 & Demo Day News - Bière & Code Paris
Read the latest update: Last Bière & Code of 2025 & Demo Day News
bierecode.com
Paired-end parsing now works with our lightweight, auxiliary FASTQ.gz indexing scheme! Now I hope to get some benchmarks and a preprint out soon.
I'm hiring for some early-mid career wet lab roles in LA we're building the cattle industries top genomics lab. www.linkedin.com/jobs/view/43... please share with socal pals! cc @nmancuso.bsky.social @docedge.bsky.social
Grimmius Cattle Company, Inc. hiring Laboratory Scientist- Genotyping in Pasadena, CA | LinkedIn
Posted 3:13:45 PM. About the RoleWe are looking for a motivated Laboratory Scientist to join the genotyping team at…See this and similar jobs on LinkedIn.
linkedin.com
We recently crossed the 1 million download mark for the Gencove CLI!!! x.com/migueliezun/...
Miguel Liezun on X: "RT @Gencove: The Gencove CLI has recently crossed the 1 million download mark 🚀 This is a testament to the reliability of our genomic analy…" / X
RT @Gencove: The Gencove CLI has recently crossed the 1 million download mark 🚀 This is a testament to the reliability of our genomic analy…
x.com
For the ones that care about their skin www.consumer.org.hk/en/press-rel...
Over 80% of Sunscreen Performed Below their Labelled Efficacy Increase the Risks of Skin Darkening, Sunburn or Even Skin Cancer | Consumer Council
The Consumer Council keens to be the trusted voice of consumers in striving to build in the market an environment of safe, fair and sustainable consumption.
consumer.org.hk
Just got this email. “invited you as a developer” 🤣 Nice try
go.dev/doc/go1.25 Go 1.25 just came out and now includes go build -asan. Which builds a binary that checks C memory leaks at program exit. This is exactly what I needed for caddy-snake
Go 1.25 Release Notes - The Go Programming Language
go.dev
www.alphaxiv.org/abs/2504.17033
Breaking the Sorting Barrier for Directed Single-Source Shortest Paths | alphaXiv
View 1 comments: This appears to be a non-standard assumption and unclear if feasible in non-exponential modification. See the corresponding discussion on StackExchange: https://cstheory.stackexchange...
alphaxiv.org
