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@mlisboaperez.bsky.social

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@mlisboaperez.bsky.social · last yr.

Very happy to see our manuscript officially published at #NatureCommunications! It was a new and exciting journey for me, previously researching on CS topics, to work on this richly multi-disciplinary project www.nature.com/articles/s41... #AI @nanoporetech.com #DNASequencing #SyntheticBiology

Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning - Nature Communications

Perez, Kimoto, Rajakumar and colleagues present a fast and accurate DNA sequencing method that reads canonical and non-canonical bases using AI and nanopore technology. The approach enables an expande...

nature.com

@mlisboaperez.bsky.social · 2y ago

Excited to share our latest work, where we show how to achieve high-throughput sequencing of DNA containing non-canonical bases using Nanopore (@nanoporetech.com) and de novo basecalling enabled by spliced-based data-augmentation. #nanopore #basecaller #syntheticbiology

Direct high-throughput deconvolution of unnatural bases via nanopore sequencing and bootstrapped learning

The discovery of synthetic xeno-nucleic acids (XNAs) that can basepair as unnatural bases (UBs) to expand the genetic alphabet has spawned interest in many applications, from synthetic biology to DNA ...

biorxiv.org