In a new study in Nature Communications, Martin Vingron and @ekindea.bsky.social present "Corgi", an AI-based tool that allows researchers to predict how the genome behaves across different cell types. Read more: www.molgen.mpg.de/news-2026-le... Original publication: doi.org/10.1038/s414...

I'm excited to share that Corgi is out in @natcomms.nature.com! We refine context-aware sequence-to-function models by using FiLM to condition the model on trans-regulator expression levels. This way Corgi can generalize to unseen cell types. www.nature.com/articles/s41... 🧵Thread 1/n

Context-aware sequence-to-function model of human gene regulation - Nature Communications

This study introduces Corgi and Corgi+ , biology-inspired deep neural network models of regulatory DNA sequences that can generalize to unseen cell types. They accurately impute epigenomic d...

nature.com

‪🧬🔬 🧪Lange Nacht der Wissenschaften 2026 Berlin auch an unserem Institut! Vorträge, Führungen durch Labore und Mitmach-Aktivitäten von unseren liebe Kolleg*innen 👩‍🔬 und für unsere tolle Gäste 👨‍👩‍👧‍👦! #LNDW

Meet the first author: We spoke with Anja Hess about her recent publication in Genome Biology by the Meissner and @vallierlab.bsky.social, the one skill she learned that she didn't expect to need, and the invisible work that went into the study. -> Read more: www.molgen.mpg.de/mtfa-anja-hess

Meet the first author: Anja Hess

molgen.mpg.de

In our "Meet the first author" series we spoke with Lisa Martina and Michal Malszycki about their recent paper, their fascination with nuclear speckles, and how an unexpected discovery helped them gain insight into the functions of speckles. www.molgen.mpg.de/news-2026-mt... @aktast.bsky.social

Johannes Stein's new lab at the MPIMG will use microscopy to study the organization of the genome at a molecular level. We talked to him about how, despite being a trained physicist, he ended up in biology, the potential of his research and the power of interdisciplinary teams. @jmstein.bsky.social

A nanoscopic look at gene regulation

Johannes Stein joined the MPIMG in 2025. His lab will use state-of-the-art microscopy techniques to examine the organisation of the genome at a molecular level. We talked to him about how, despite bei...

molgen.mpg.de

A new study shows how different regulatory genetic elements coordinate the activity of a key developmental gene. The findings could explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown. Read more: ⬇️

Waves of regulation control an important developmental gene

In a new study published in Genes & Development, researchers from the labs of Stefan Mundlos (Max Planck Institute for Molecular Genetics and Charité, Berlin) and Lila Allou (MRC Laboratory of Medical...

molgen.mpg.de

We are excited that Claudia Langenberg and Malte Spielmann joined the MPIMG this year as external scientific members of the Max Planck Society. These roles are held by researchers with close MPI ties, strengthening our network and fostering collaboration. Read more: www.molgen.mpg.de/news-2026-ex...

Raquel Fueyo's lab studies the impact of transposons on human embryonic development and disease. We talked with her about what drew her to this field, her lab's work culture, and how she finds inspiration for her science in art. @fueyoraquel.bsky.social Read more: www.molgen.mpg.de/news-2026-in...

"I find artists' creativity inspiring, and I hope to apply some of it to science"

molgen.mpg.de

Congrats to @elisamoutin.bsky.social, Postdoc @vallierlab.bsky.social, on receiving a Marie-Sklodowska-Curie Postdoct Fellowship. Elisa will study how genetic and epigenetic alterations in chronic liver disease drive hepatocyte–cholangiocyte transdifferentiation and contribute to cancer.

On March 10, we hosted a panel discussion for International Women's Day on unconscious bias in academia. We discussed how bias affects hiring and women’s workload. Solutions like anonymized applications and diverse panels trained on DEI were proposed for a more inclusive future. #IWD #WomeninSTEM

Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Last but not least Postdoc Petar Glazar from the lab of @aktast.bsky.social. His role model is Ada Yonath, crystallographer and Nobel laureate. #IWD2026

Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Today Postdoc Irene Talon from the Vallier Lab. #InternationalWomensDay #IWD2026 #WomenInScience

Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Today Katarina Ninkovic about her role mode, American microbiologist Alice Catherine Evans.

Congratulations to director Alexander Meissner, who has been honored with the 2026 ISSCR Momentum Award for Exceptional Work in Developmental and Stem Cell Epigenetics by the The International Society for Stem Cell Research. @isscr.org --> Read more: www.molgen.mpg.de/news-2026-is...

Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Today Marcel Wittmung (Hnisz/Vingron Labs) and his role model Debbie Marks.

Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Today Hannah Wieler and her role model Hedi Lamarr—actress and inventor who's ideas set the basis for many modern technologies. #IWD2026 #WomenInScience

New paper in @cellpress.bsky.social by the Aktas lab @aktast.bsky.social! The scientists show that nuclear speckles help process RNA transcribed from dense regions of the genome, providing an answer to the long-standing question of speckle function. Read more: www.molgen.mpg.de/news-2026-nu...

Thanks to everyone who joined us at the 2nd Meeting on Early Embryogenesis & Epigenetics last week—great talks and valuable discussions across the community! Huge thanks to our partners at the Weizmann, the speakers, session chairs, and all the behind-the-scenes helpers! www.molgen.mpg.de/embryo2026

Last but certainly not least, the final guest speaker at the 2nd meeting on embryogenesis and epigenetics will be Joanna Wysocka from Stanford University. We look forward to hearing about her work on human development and evolution. More information: www.molgen.mpg.de/embryo2026

Next in our featured speakers for the 2nd meeting on early embryogenesis & epigenetics: Alexander van Oudenaarden of the Hubrecht Institute will discuss his work on novel sequencing tools for exploring translation in individual cells. More information: lnkd.in/eGGGDXHz

Thank you for all of the applications submitted to the IMPRS-BAC graduate school! We are currently evaluating them and will notify candidates by the end of January. Good luck, and thank you for your interest! The next call will open in October 2026. @freieuniversitaet.bsky.social

🧬 Only one month until the 2nd meeting on early embryogenesis & epigenetics. #Embryo2026 Barbara Treutlein (@ethz.ch) will speak about her work reconstructing human brain development with organoids and single-cell technologies! More information: www.molgen.mpg.de/embryo2026

📢 LAST CALL! Celebrate the New Year by applying for one of our #PhD projects & #IMPRS-BAC #gradschool until Jan 7th, 2026! 👉 www.molgen.mpg.de/IMPRS/applic...

📆 Holiday Season is coming up, so there is plenty of time to prepare your application for the #IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/IMPRS/applic...

Next in our featured speakers for the 2nd meeting on early embryogenesis & epigenetics: Amos Tanay (Weizmann Institute of Science) will speak about quantitative models for the epiblast and beyond. More information: www.molgen.mpg.de/embryo2026

We look forward to welcoming Kikuë Tachibana (Max Planck Institute of Biochemistry) to the 2nd Meeting on early embryogeneis & epigenetics! More information: www.molgen.mpg.de/embryo2026

🧬 Are you interested in synthetic biology, CRISPR-Cas9 genome editing and cutting-edge genomics? Apply by 07.01.2026 to join Stefan Mundlos’ lab @stemundi.bsky.social at the MPIMG. #IMPRS-BAC #gradschool! @nataliabenetti.bsky.social 👉 www.molgen.mpg.de/5124667/Mund...

📢 Speaker showcase for our 2nd Meeting #Embryo2026 🧬 Marta Shabhazi (MRC Laboratory of Molecular Biology / University of Cambridge) will speak about the developmental plasticity of the early human embryo. More information: www.molgen.mpg.de/embryo2026

🧬 Are you fascinated by alternative splicing? Join Florian Heyd’s lab @freieuniversitaet.bsky.social & #IMPRS-BAC #gradschool for your PhD! Strong background in molecular biology and cell culture needed. 👉 www.molgen.mpg.de/5120514/Heyd...