Next week on Fragile Nucleosome: 🧬 Pavan Choppakatla from the Levine lab will share his work on long-distance enhancer-promoter search 🧬 @moorejille.bsky.social will tell us about millions of enhancers in the registry of candidate CREs Register here and join us!: us06web.zoom.us/webinar/regi...

These data display regions identified by biochemical signatures predicted to regulate gene expression as promoters, enhancers, or other regulatory elements. We would like to thank Zhiping Weng, and Jill Moore for their work in producing and displaying these data.

A UMass Chan-led research team has nearly tripled the known number of potential regulatory elements in the genome to 2.37 million. Read about the paper, published in @nature.com, on the new registry: direc.to/oouM #genome #epigenetics #CRE @moorejille.bsky.social @zhipingweng.bsky.social

UMass Chan scientists annotate largest map yet of human genome’s regulatory switches

A UMass Chan-led research team has nearly tripled the known number of potential regulatory elements in the genome to 2.37 million.

direc.to

Our paper on the Expanded Registry of candidate cis-Regulatory Elements (cCREs) is out 🎉 www.nature.com/articles/s41... To celebrate, here’s a "meme-torial" walkthrough of the science. Let’s get started 🧵 1/11

a man wearing a plaid shirt and a purple hat is saying here we go .

ALT: a man wearing a plaid shirt and a purple hat is saying here we go .

media.tenor.com

Our paper on the newest version of the Registry of candidate cis-Regulatory Elements (cCREs) is out 🧬 Huge thanks to the many collaborators, experimentalists, analysts and software developers who made this work possible — truly a team effort! A "meme-torial" of the science is coming soon 👀

An expanded registry of candidate cis-regulatory elements - Nature

The existing ENCODE registry of candidate human and mouse cis-regulatory elements is expanded with the addition of new ENCODE data, integrating new functional data as well as new cell and tissue types...

nature.com

Going to #ASHG25? Don’t miss our FREE interactive workshop on Investigating Non-Coding Regions with SCREEN and Factorbook. Wed Oct 15 @ 11:45 am, Room 104C (level 1) 🧬 Lunch included! 🧬

Excited that we will be co-leading the DAC with @ZhipingWeng (fearless leader) @MooreJillE & @thabangh for the new Multiomics for heath and disease consortium. www.nih.gov/news-events/...