Our new preprint on promises and caveats of the extraction of M/EEG activity from ROIs is out (see more details in the reposted thread): www.biorxiv.org/content/10.6... Huge thanks to @studenova.bsky.social, Ruben Eguinoa, Guido Nolte, @sparsity.bsky.social, Arno Villringer, and Vadim Nikulin!

Non-uniform effects of remaining field spread on the estimation of M/EEG activity and connectivity between regions of interest

In M/EEG analyses, it is often convenient to extract time series of activity originating from the regions of interest (ROIs). However, due to the spread of electric and magnetic fields, M/EEG recordin...

biorxiv.org

Alina Studenova@studenova.bsky.social · 8mo ago

I use EEG/MEG. When I meet like-minded researchers at conferences, the discussion always circles back to one thing: admitting that results may be confounded by leakage (also known as remaining field spread—RFS). In our new preprint, we quantify RFS in parcellated data using cross-talk function—CTF.🧵

Parkinson’s disease involves two major abnormalities in subthalamic nucleus activity: 1️⃣ Excessive beta (13–30 Hz) rhythms 2️⃣ Increased neuronal firing Beta can be measured 𝗮𝗳𝘁𝗲𝗿 surgery using deep brain stimulation electrodes.

Deep brain stimulation can improve Parkinson’s disease symptoms, but selecting the optimal stimulation contact still relies on laborious trial-and-error.

A neuron can only do two things: Fire. Don’t fire. Firing is the neuron’s output, and most theories of neural computation treat that output as the brain's core information signal. 🧵

Imagine you run an experiment with 50 subjects and find a significant effect just below p < 0.05. Another research group tries to replicate your finding, so they also recruit 50 people. If your methodology was perfect, what’s the chance the replication succeeds? 95%? 80%? It’s only 50% 🤯 👇🧵

Ming Tommy Tang@tommytang.bsky.social · 10mo ago

🧵 Why the obsession with p < 0.05 is hurting science.

Thank you @mpicbs.bsky.social for covering our study! And thank you for fostering such an inspiring, intellectually vibrant, and genuinely supportive research environment — it was an exceptional place to do a PhD 🙏

Max Planck Institute for Human Cognitive and Brain Sciences@mpicbs.bsky.social · 9mo ago

Noise as a Signal – Moritz Gerster, Vadim Nikulin & Arno Villringer analysed data from 119 patients & discovered a new electrical signature of #Parkinson’s Disease, now published in @ebiomedicine.bsky.social: www.cbs.mpg.de/2412209/2025... #parkinsontherapy #clinicalstudy

Now out in @ebiomedicine.bsky.social! 📖 Read the open-access article: authors.elsevier.com/sd/article/S... #Neuroscience #Neurology #Parkinsonsdisease #Parkinsons #DeepBrainStimulation #DBS #Neurotechnology #Neuromodulation #Neurophysiology #BasalGanglia #OpenScience #Reproducibility

Moritz Gerster@moritz-gerster.bsky.social · last yr.

How does subthalamic activity relate to Parkinson’s disease symptoms? In a truly collaborative effort across #DBS centers, we aggregated a diverse dataset of invasive recordings from 119 patients. Full article: doi.org/10.1101/2025... Main findings 🧵⬇️

How does subthalamic nucleus activity relate to Parkinson’s disease symptoms? My last 5 years of Parkinson’s disease research summarized in 5 minutes at the DGKN Congress 2025 :) youtu.be/M9alDh836oU ⬇️ Full preprint: doi.org/10.1101/2025... #Parkinsonsdisease #Parkinsons #DeepBrainStimulation

Beyond beta rhythms - Moritz Gerster at DGKN Congress 2025

YouTube video by Moritz Gerster

youtu.be

How does subthalamic activity relate to Parkinson’s disease symptoms? In a truly collaborative effort across #DBS centers, we aggregated a diverse dataset of invasive recordings from 119 patients. Full article: doi.org/10.1101/2025... Main findings 🧵⬇️

We were blown away by the public response to our findings that the infant brain can store memories. Many people wrote to share with us their first memories. To help us capture these reports, we created a short, anonymous survey. We hope you might also consider taking it. Please share with others! 🧠🧪

Tristan Yates@tristansyates.bsky.social · last yr.

Why do we not remember being a baby? One idea is that the hippocampus, which is essential for episodic memory in adults, is too immature to form individual memories in infancy. We tested this using awake infant fMRI, new in @science.org #ScienceResearch www.science.org/doi/10.1126/...

Excited to have my PhD project paper exploring the network mechanisms of neuromodulation accepted for publication! We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.