We are absolutely thrilled to have arrived in our new offices at the Department of Mathematical Modeling and Machine Learning of the University of Zurich @uzh-ch.bsky.social . Big thanks to our new colleagues for the warm welcome! 🙏 We look forward to shaping the future of AI in Science together!
Sbalzarini Lab / MOSAIC Group
@mosaicgroup.bsky.social
We advance scientific machine learning and physics-informed AI for the sciences. We are at the Department of Mathematical Modeling and Machine Learning @uzh-ch.bsky.social. Posts by Ivo Sbalzarini. https://sbalzarini-lab.org
Our work @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de @scadsai.bsky.social fuses representation learning with spatial statistics @iclr-conf.bsky.social enabling #AI for spatial localization patterns: openreview.net/forum?id=09Y...
Spatially Informed Autoencoders for Interpretable Visual...
We introduce spatially informed variational autoencoders (SI-VAE) as self-supervised deep-learning models that use stochastic point processes to predict spatial organization patterns from images....
openreview.net
Modeling spatial point patterns from noisy, incomplete experimental data just got easier! Great work by @domsturm.bsky.social for sparse, noise-robust model inference of point processes 🤩 @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de Preprint out now: arxiv.org/abs/2510.25550
Robust variable selection for spatial point processes observed with noise
We propose a method for variable selection in the intensity function of spatial point processes that combines sparsity-promoting estimation with noise-robust model selection. As high-resolution spatia...
arxiv.org
🤩👍🏼💪🏼 Meet #TopoSPAM - a high-performance simulation platform for biological morphogenesis with a friendly Python interface. @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de. Solve both continuous and discrete active mechanics! Released today: arxiv.org/abs/2509.24905
TopoSPAM: Topology grounded Simulation Platform for morphogenesis and biological Active Matter
We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with ad...
arxiv.org
🤩🤩🤩Absolutely thrilled our work is featured in the Magazine of @maxplanck.de ! Big thanks to the writer and editor 🙏🙏🙏 Never saw our work described so well! Curious? @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de - PDF is freely available, article starts p.36: www.mpg.de/25430399/MPR...
mpg.de
In a beautiful team effort, we wrote a comprehensive review of meshfree collocation methods for numerically solving PDEs @csbdresden.bsky.social @uni.lu #CVUTPrague @tudresden.bsky.social Preprint out now: arxiv.org/abs/2509.20056
An Overview of Meshfree Collocation Methods
We provide a comprehensive overview of meshfree collocation methods for numerically approximating differential operators on continuously labeled unstructured point clouds. Meshfree collocation methods...
arxiv.org
It was a pleasure to speak at #BuildingBridges2025. Germany, Poland, Hungary, and Lithuania - together in one session on #Biomedical #AI. Great also to meet so many friends again! Big thanks to the organizers for inviting me! 🙏🙏🙏🙏 @hzdr.bsky.social @tudresden.bsky.social
🙏 Very honored to speak at #BuildingBridges2025 on #AI for #Biomedicine. What an amazing lineup of panelists 🤩🤩🤩 Politics and Science working together- Germany, Lithuania, Czech Republic, Poland - together for future #AI 👍🏼 @hzdr.bsky.social @csbdresden.bsky.social
Looking forward to present on the topic of AI for Biomedicine tomorrow!
The Building Bridges Conference 2025: Latest Findings in Artificial Intelligence kicked off today, bringing together researchers, policymakers and industry leaders from across Europe. #BuildingBridges2025
#GoGAIN25: 🌎 From August 29 to 31, #TUDresden will be in #Boston with @daadworldwide.bsky.social, @humboldt-foundation.de & @dfg.de, presenting a series of talks & hosting a booth to showcase our University of Excellence & the city of Dresden as a hub for science. 🧑🔬 ℹ️ tu-dresden.de/internationa...
This👇is fantastic work! Congratulations @loicaroyer.bsky.social and team!!
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods! 📦 Ultrack — robust, scalable nD cell tracking 🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration Let’s dive in! 👇 www.nature.com/articles/s41... www.nature.com/articles/s41...
#GenAI meets perception psychology for better super-resolution microscopy 🤩 Fig.1 says it all! 😎 Fantastic collaboration with @casusscience.bsky.social - work of @zuseschoolsecai.bsky.social students @csbdresden.bsky.social - out now onlinelibrary.wiley.com/doi/10.1002/...
🚨Fundamental computer science result! 🤩🤩🤩 Particle Methods, a class of algorithms, can compute anything that is computable, even when severely resource restricted ‼️‼️Formally proven result @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de now out: fi.episciences.org/16055
On the Computational Power of Particle Methods
We investigate the computational power of particle methods, a well-established class of algorit hms with applications in scientific computing and computer simulation. The computational power of a comp...
fi.episciences.org
To learn more about the people behind this work, we caught up with first author Justina Stark, and corresponding authors Ivo Sbalzarini (@mosaicgroup.bsky.social @csbdresden.bsky.social) and Michael Brand (@tudresden.bsky.social): journals.biologists.com/dev/article/...
Read the #OpenAccess Research Article "Morphogen gradients are regulated by porous media characteristics of the developing tissue" here: journals.biologists.com/dev/article/...
Thanks for the highlight @dev-journal.bsky.social !! 🙏🙏🙏
Mind the pores: studying morphogen gradients Read this Research Highlight showcasing work from Justina Stark, Rohit Krishnan Harish, Ivo Sbalzarini @mosaicgroup.bsky.social and Michael Brand @tudresden.bsky.social: journals.biologists.com/dev/article/...
Tagging @mpi-cbg.de @poldresden.bsky.social
⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...
⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...
Morphogen gradients are regulated by porous media characteristics of the developing tissue
Summary: Image-based 3D modeling of pore-scale extracellular space geometries of the developing zebrafish embryo reveals that the Fgf8a morphogen gradient is regulated by the porous media characterist...
journals.biologists.com
Our scientific computing framework #OpenFPM now has multistage and adaptive time integrators that scale to distributed CPU clusters and GPUs! Happy supercomputing! @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de preprint: arxiv.org/abs/2309.05331
Integrating Odeint Time Stepping into OpenFPM for Distributed and GPU Accelerated Numerical Solvers
We present a software implementation integrating the time-integration library Odeint from Boost with the OpenFPM framework for scalable scientific computing. This enables compact and scalable codes fo...
arxiv.org
🔥🔥🔥Unique opportunity! We are looking for a new Max Planck Director in Biomedical #AI. Max Planck Research Directors enjoy unparalleled freedom and resources. And the best: you’d get to work with us here at the @csbdresden.bsky.social in the heart of the vibrant @tudresden.bsky.social AI campus!
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Formulas of Life: article of the @maxplanck.de on the research of Ivo Sbalzarini @mosaicgroup.bsky.social. Article in German language: www.mpg.de/24841408/ki-...
Formeln des Lebens
Künstliche Intelligenz mit physikalischem Vorwissen soll biologische Vorgänge berechenbar machen
mpg.de
Ivo Sbalzarini was interviewed by German science radio @detektorfm.bsky.social and explains our research @csbdresden.bsky.social @mpi-cbg.de @tudresden.bsky.social to a general audience (in German only): detektor.fm/wissen/forsc...
Wie kann Künstliche Intelligenz in der Biomedizin helfen?
Biologie und Medizin sind eng verknüpft. Künstliche Intelligenz kann dabei in vielen Fragen helfen. Was ist zu beachten?
detektor.fm
🔥Just out @EGPGV’25: Parallel visualization of distributed volume data for non-convex decompositions! @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de And the best: code is contributed upstream 🤩 diglib.eg.org/items/3aed38...
A Transparent and Efficient Extension of IceT for Parallel Compositing on Non-Convex Volume Domain Decompositions
The IceT library is widely used for parallel compositing but does not support non-convex volume domain decompositions. We provide a backward-compatible extension of IceT to handle non-convex domain de...
diglib.eg.org
Fantastic! 🤩 Best success ever for our university!! This is going to enable sooooo much cool new research in the coming years. The sky is the limit!
Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century. ℹ️ tu-dresden.de/tu-dresden/n...
Proud and happy our group could be involved in this. Congratulations, Roua!
Revisions were a crazy ride & would never have been possible without the endless efforts by @cryaaa.bsky.social & Alba, as well as all the new collaborators that helped with experiments and modelling: Roua Rouatbi @mosaicgroup.bsky.social @csbdresden.bsky.social, Kathrin Schmeisser @ Rodenfels lab
APR-CNN: Convolutional Neural Networks for the Adaptive Particle Representation of Large Microsco... Joel Jonsson, Bevan Leslie Cheeseman, Ivo Sbalzarini Action editor: Moshe Eliasof https://openreview.net/forum?id=5qKI2dkrjL #cnn #cnns #microscopy
It was great hosting and meeting Sophie Jaffard @csbdresden.bsky.social @tudresden.bsky.social. We look forward to many more discussions on the mathematics of neural networks in neuroscience and in machine learning!
And Sophie Jaffard, also a PhD student from the Université Côte d’Azur in Nice visited Türkü Özlem Çelik and @mosaicgroup.bsky.social to discuss her work on mathematical models of biologically inspired neural networks 🧠
Enabling deep learning on large images with massively reduced compute and resource needs. Meet the content-adaptive APR-CNN architecture! Out now in @tmlrorg.bsky.social - openreview.net/forum?id=5qK...
APR-CNN: Convolutional Neural Networks for the Adaptive Particle...
We present APR-CNN, a novel class of convolutional neural networks designed for efficient and scalable three-dimensional microscopy image analysis. APR-CNNs operate natively on a sparse...
openreview.net
Congratulations, Tommaso! It was a great PhD defense!!!
Congratulations Tommaso for an excellent PhD defense! Very well done!