Lots of great ideas at the Alport Syndrome Research Regulatory workshop held two weeks ago. Looking forward to seeing what we can achieve next. alportsyndrome.org/wp-content/u...
Our review on podocytes in health and glomerular disease: www.frontiersin.org/articles/10....
Frontiers | Podocytes in health and glomerular disease
frontiersin.org
Are you a PhD or MD PhD in medical science or related discipline? If you are interested in a postdoctoral research fellowship, there is a great opportunity @uhntoronto.bsky.social. And contact me if interested in studying kidney disease: www.uhn.ca/corporate/Ab...
UHN Canada Leads 100 Challenge
Join the Canada Leads 100 Challenge at UHN! Support the recruitment of leading early career scientists and help shape the future of medical research in Canada.
uhn.ca
Congratulations to Professor Kai at #KumamotoUniversity for bringing together the #AlportSyndrome community in Japan to advance efforts in awareness, early diagnosis and therapeutic development. I was honoured to be a small part of it.
Having a fabulous Bluesky day in Japan! Trip to Minamata with team #Alport & family @moumitabarua.bsky.social @jeffminerphd.bsky.social @alportuk.bsky.social
How does gene variant influence mechanism in Alport syndrome? We became interested in learning about this in trying to understand how to approach precision based therapeutics. Read our review by Bilge Çaparali, MD and Vanessa De Gregorio, MSc journals.lww.com/jasn/abstrac...
Human genetic studies have highlighted type IV collagen as critical for kidney filtration function--I am looking forward to learning from and participating in this workshop on Alport syndrome.
A fruitful collaboration utilizing data in UK Biobank to NEPTUNE and more--highlights a genetically predicted exon skipping event in collagen IV as a contributor to glomerular hematuria. journals.lww.com/jasn/fulltex...
Association of Genetically Predicted Skipping of COL4A4... : Journal of the American Society of Nephrology
out affects collagen IV trimer assembly and secretion. Background Hematuria is an established sign of glomerular disease and can be associated with kidney failure, but there has been limited scient...
journals.lww.com
Our spotlight on collagen- formation, function & role in kidney disease is out now! A wonderful collaboration with Moumita Barua & Vanessa De Gregorio #ECMatrix #Nephro Cell-Matrix Centre @fbmh-uom.bsky.social @uoft.bsky.social www.nature.com/articles/s41...
Collagen formation, function and role in kidney disease - Nature Reviews Nephrology
Collagens are ubiquitously expressed and have been linked to a broad spectrum of disorders. Here, the authors discuss collagen subtypes and provide a summary of collagen disorders, fibrotic process an...
nature.com