Max Planck Institute of Colloids & Interfaces (MPICI)

@mpici.bsky.social

Exploring the world of 'hidden dimensions' ( #colloids & #interfaces ) and bridging the gap between #molecules, #MultiScaleMaterials, and #BioSystems. In Potsdam, #Germany. https://www.mpikg.mpg.de/departments #chemsky #Forschung #Research

We are excited to announce that the next generation of sustainable materials will be inspired by nature: Our new #IMPRS for Functional Material Design will welcome 23 fully funded doctoral candidates starting in winter 2026/27. @maxplanck.de More information ➡️ www.mpikg.mpg.de/new-impres-f...

Learning from Nature: New IMPRS for Functional Material Design

Functional Material Design graduate school fosters research at the intersection of physics, chemistry, biology, and materials science.

mpikg.mpg.de

De novo design of glycan foldamers with programmable tertiary structure out today in @jacs.acspublications.org Congrats to Yadiel! With Nishu Yadav, Martin Rosenthal and Yu Ogawa @mpici.bsky.social @cermav.bsky.social pubs.acs.org/doi/10.1021/...

De Novo Design of Glycan Foldamers with Programmable Tertiary Structure

De novo molecular design has yielded proteins and peptides with structures and functions beyond those found in nature. Despite the potential for glycans to form a broader scope of well-defined tertiary architectures, owing to the numerous conjugation sites and stereocenters, no one has yet built glycans with targeted structures and functions from scratch. Here, we designed glycan sequences that fold into programmable 3D architectures. Starting from first-principles, we create a linear glycan that spontaneously adopts a rigid tertiary structure not reported for natural glycans. Considering stereochemical and spatial orientation, we identify a rigid trisaccharide turn unit that programs backbone directionality, driving folding into antiparallel geometry. The combination of this turn unit with multiple cellulose-like strands completes our design, stabilizing a tertiary sheet-like folding, as confirmed by nuclear magnetic resonance spectroscopy and small-angle X-ray scattering (SAXS). To quantitatively evaluate the conformational landscape of our glycans in aqueous solution, we built a semiautomated protocol that integrates SAXS data with molecular dynamics simulations, demonstrating further the effectiveness of our design principles. This is an important step to design and control conformation populations, not just single structures in the solid state or of unknown prevalence in the solution phase. Together, these results show that glycans can be programmed to adopt rigid tertiary structures on demand, opening new avenues for de novo glycan-based architectures in synthetic glycobiology, catalysis, and materials science.

pubs.acs.org

What does a "self-driving lab" look like & how could #sugars shape the future of #medicine? In BMS labs, #AI & #automation predict & execute #carbohydrate synthesis, enabling new #vaccines & diagnostic tools. Long-term vision: remote drug factories w/ limited infrastructure. tinyurl.com/535pvpm4

The Future of Medicine: Automating Chemistry with Peter Seeberger

In this episode of "On The Go," we visit the Max Planck Institute of Colloids and Interfaces to meet Peter Seeberger, a visionary chemist and entrepreneur who is transforming the world of medicine. Discover how Peter and his team are automating the complex process of synthesizing carbohydrates (sugars), reducing a task that once took years to just a single day. We explore the cutting-edge Artemiflow technology and the concept of a "self-driving lab"—where AI and automation work 24/7 to predict and execute chemical reactions with unprecedented precision. 0:00 Intro: Meet Peter Seeberger 0:31 Automation vs. Traditional Chemistry 1:18 The Carbohydrate Synthesis Revolution 2:02 How the "Sugar Machine" Works 2:46 From "Bucket Chemistry" to Flow Reactors 3:30 Artemiflow: Real-World Medical Impact 4:15 The Concept of the "Self-Driving Lab" 5:03 Decentralized Medicine: Pharmacies in a Container 5:45 Is Automation a Threat to Jobs? 6:24 The Future: Curiosity-Driven Science 7:05 Outro: Scaling Innovation from Germany In this video, you'll learn about: The revolutionary machine that automates carbohydrate synthesis. How "sugar chemistry" is being used to develop new vaccines and diagnostic tools. The move from "bucket chemistry" to "pipe chemistry" (flow reactors) for safer, more efficient production. Peter’s vision for remote drug factories that could provide life-saving medications to countries with limited pharmaceutical infrastructure. Is automation a job killer for chemists, or the key to a more competitive and innovative future? Join us for an inspiring look at how curiosity-driven science is solving global challenges. Hashtags #Chemistry #Innovation #Automation #MaxPlanckInstitute #DrugDiscovery #Vaccines #Biotech #PeterSeeberger #Artemiflow #FutureOfMedicine #ScienceCommunication #Entrepreneurship

tinyurl.com

An event to look forward to in #2026: our PhDs & postdocs are organizing a symposium to share research approaches, pitch ideas, & connect. Researchers from >40 countries & 4 depts—all drawing inspiration from nature to tackle technological challenges = perfect recipe for an inspiring get-together!

Laura Zorzetto@laurazorzetto.bsky.social · 8mo ago

April is still far, but gears are already turning to organize the 2026 Symposium for PhD and Postdocs at @mpici.bsky.social. Stay tuned! #PhDlife #Postdoclife #MPIKG

Flyers adversiting the 2026 PhD and Postdoc symposium of MPIKG