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Matthew A. Mulvey

@mulveylab.bsky.social

Matthew A. Mulvey, Ph.D. Host-Pathogen Interactions + bugs, birds, and other carbon-based lifeforms. https://www.biology.utah.edu/faculty/matthew-mulvey/

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Matthew A. Mulvey@mulveylab.bsky.social · 3mo ago

Check out our new pub with @amweis.bsky.social, O'Connor Matthews & Round lab!! @uofubiology.bsky.social Isolation of a highly virulent colibactin-positive tumor-promoting strain of Escherichia coli from the gut microbiota of an adult | mSphere journals.asm.org/doi/10.1128/...

Isolation of a highly virulent colibactin-positive tumor-promoting strain of Escherichia coli from the gut microbiota of an adult | mSphere

Colorectal cancer (CRC) is a significant burden on human health. A growing body of work has pointed to critical roles for microbes in the exacerbation of and protection from the development of CRC. Specific Escherichia coli strains can produce colibactin, a genotoxin that has been implicated in exacerbating CRC. In this study, we tested human microbiotas in a mouse model of CRC and isolated a colibactin-positive Escherichia coli strain that led to tumorigenesis, disseminated from the gut to the mouse kidneys, caused death, and worsened both colitis and sepsis in murine models. Identification of this strain enhances our collective knowledge and adds an important tool for future studies on the role of microbes and CRC tumorigenesis.

journals.asm.org

Matthew A. Mulvey@mulveylab.bsky.social · 9mo ago

Mulvey lab alumna Alexis Rousek taking on UTIs with the Student Research Initiative at the U of Utah. science.utah.edu/sri/sri-stor... @uofubiology.bsky.social @globaluti.bsky.social #UTIGA

SRI Stories: Mentoring Through Microbes | College of Science

SRI Stories: Mentoring through Microbes October 15, 2025 Above: Alexis Rousek Alexis Rousek didn’t always know she would become a microbiologist — but the signs were there early. In middle school, she...

science.utah.edu