Value of repeat LP in uncertain diagnosis, especially without pleocytosis. Repeat Lumbar Puncture in Adults With Encephalitis: Patient Characteristics, Cerebrospinal Fluid Dynamics, and Diagnostic Yield academic.oup.com/ofid/article...

Repeat Lumbar Puncture in Adults With Encephalitis: Patient Characteristics, Cerebrospinal Fluid Dynamics, and Diagnostic Yield

We describe characteristics of patients with encephalitis who receive repeat lumbar punctures (LPs) during hospitalization and analyze cerebrospinal fluid

academic.oup.com

Petition to expel Israeli ambassador. I try not to wade into the political sewer but I really want to share this. One more post and normal programming may resume. www.aph.gov.au/e-petitions/...

e-petitions

e-petitions

aph.gov.au

Gastro with EPEC brings longer LOS in adults, and paradoxically shorter in paeds. link.springer.com/article/10.1...

you know how crucial new antibiotics are? scientists just added 118 previously unknown myxobacteria – tiny microbes that make natural drug compounds – to our arsenal. it's like suddenly having 118 new blueprints for fighting resistant infections, made public for all researchers.

Study Reveals Hidden Myxobacteria Diversity for Future Drug Discovery

Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have significantly expanded the known biological diversity of myxobacteria, a crucial source of natural antibiotic co

news-medical.net

CARB-X Executive Director Kevin Outterson will testify today as a witness at a Senate Finance Committee Subcommittee on Health Care Hearing. Antibiotics are essential healthcare infrastructure, yet they remain undervalued and underinvested in. #PoliSky 🎥 bit.ly/45D0AuM

Let's stop doing empiric therapy trials. We know the pathogen (mostly) in 1hr now. No more superfluity. Clinical outcomes of beta-bactam monotherapy versus beta-lactam plus azithromycin in hospitalized patients with community-acquired pneumoniae academic.oup.com/jac/article-...

Clinical outcomes of beta-bactam monotherapy versus beta-lactam plus azithromycin in hospitalized patients with community-acquired pneumoniae

AbstractBackground. We aim to assess the clinical efficacy of β-lactam plus azithromycin compared with β-lactam monotherapy in the empirical treatment of c

academic.oup.com

You’ll never know if you’ll break the 2nd album curse if you don’t release the first. Get to it.

This really is "new guideline" work!

Josh Davis@gurujosh.bsky.social · 3mo ago

Calling all data scientists! Come and work with the world-leading SNAP trial team at University of Newcastle, HMRI and the Doherty Institute. Please tell all your data nerd friends and colleagues! www.livehire.com/careers/univ...

The call of the deluded: “this is how we’ve always done it” Habits can help us, and also hurt us. I'm also concerned that this may give fuel to the anti-vax group, who I continue to "fight in the trenches" www.medscape.com/viewarticle/...

The COVID Vaccine Study the CDC Doesn’t Want You to See

Higher-ups at the CDC blocked publication of a COVID vaccine effectiveness study, citing methodologic weaknesses. Now the study has been published for all to read.

medscape.com

Your first Trillion is the hardest.

WE DON’T NEED A FUCKING TREATMENT WE HAVE A VACCINE THAT IS 97% EFFECTIVE AND COULD ERADICATE THE DISEASE IF WE DIDN’T HAVE ANTIVAX GRIFTERS LEADING US 🤦🏻‍♂️🤦🏻‍♂️🤦🏻‍♂️ www.nytimes.com/2026/06/11/w...

With Measles Roaring Back, the Search for a Treatment is On

nytimes.com

1 in 5 global deaths are from sepsis. We need to push those numbers DOWN. The role of rapid and advanced microbiological methods in critical care: 2025 Emanuele Russo Delphi consensus - Clinical Microbiology and Infection www.clinicalmicrobiologyandinfection.org/article/S119...

A little summary of some events. Version 1.

In the highly/rightly quantitative ED, don't forget the qualitative: whether the patient felt seen... Thanks @andrewjtagg.bsky.social insightplus.mja.com.au/2026/18/zen-...

Zen and the art of emergency medicine

In the high tech, fast paced world of the emergency department, how do we ensure we hold onto our humanity?

insightplus.mja.com.au

A recent real‑life Emergency Department (ED) study shows rapid multiplex PCR improves patient experience through earlier pathogen clarity, fewer unnecessary antibiotics, and more confident clinical decisions. http://share.biomerieux.com/KHAbtXiRRopp

#ESCMIDGlobal 2026 🌍in Munich; April 17–21 Come to Booth A70 — see how we help Antimicrobial Stewardship 💊 with innovations across microbiology, syndromic molecular, data & One Health Preview, & details on our two Integrated Symposia: info.biomerieux.com/escmid-2026....

Great work by WA Govt to be preparing for winter. www.wa.gov.au/government/m...

Comprehensive plan for Western Australians' healthcare this winter | Western Australian Government

The Cook Government has launched its 2026 Winter Strategy, providing Western Australians early insight into measures planned to manage the public hospital system in the high-impact respiratory illness...

wa.gov.au

Mo Yin with David Paterson briefing the #AMR2026 audience on their tremendous work across all of Asia to improve outcomes for patients with MDR infections (28d mortality 27-42%). Implementation science for the adoption of BioFire to drive treatment decisions in 2-3 hours instead of 2-5 days.

Day 2 at #AMR2026: most/all prescribing should be directed by diagnostic test results, and my colleague Bruce Altevogt pointed out that many AMS guidelines don’t mention diagnostics at all. He also notes that “AMS is Health Security” - at a population and societal level.

Kicking off the #AMR2026 Jane Halton just gave the war cry to fight cookers in the social media trenches. Don’t let the inaccurate voices amplify. TO WAR!!

This week in Australia: we won two Winter Olympics Gold medals ⛷️🥇 🏂 🥇; we lost a game of cricket 🏏 against Zimbabwe, and the central player in 💧Watergate💧 (an $80M fraud 💰 against the federal govt) was elected as the leader of the Liberal party. Say it again, Maggie…

a cartoon of maggie simpson laying on bart simpson

ALT: a cartoon of maggie simpson laying on bart simpson

media.tenor.com

"Gives me the shits" is actually TRUE!!! How Chronic Stress Disrupts the Gut Microbiome www.medscape.com/viewarticle/...

How Chronic Stress Disrupts the Gut Microbiome

New research reveals how chronic stress alters the gut microbiome, fueling imbalances that may raise disease risks.

medscape.com

A fool and their money are soon parted... What ‘Secret Shoppers’ Discovered About IV Hydration Spas www.medscape.com/viewarticle/... www.medscape.com/viewarticle/...

What ‘Secret Shoppers’ Discovered About IV Hydration Spas

Researchers posed as potential clients to examine the practices and regulation of the burgeoning intravenous hydration spa industry.

medscape.com

"Diagnostic disparities in ambulatory care" - solving these with POC multiplex Resp PCR - no need for a lab!! The silent surge: the under-recognised burden of respiratory syncytial... www.sciencedirect.com/science/arti...

The silent surge: the under-recognised burden of respiratory syncytial virus, human metapneumovirus, and parainfluenza viruses in adults

Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and parainfluenza viruses (PIV) drive substantial morbidity in adults, yet remain und…

sciencedirect.com

Great piece of work by the RCH Melbourne Team. These kids need all the help they can get! pubmed.ncbi.nlm.nih.gov/40751318/

Utility of BioFire FilmArray Pneumonia Panel Plus in a High-Risk Cohort: Children Post Allogeneic Stem Cell Transplantation - PubMed

In conclusion, we report the first prospective evaluation of the diagnostic performance of the FA-PP in BAL, in a high-risk paediatric HCT cohort. We demonstrate that the FA-PP is a potentially useful...

pubmed.ncbi.nlm.nih.gov

I know who needs to see this... It's the vast majority of presenters that I have seen recently start their PPT show with Presenter View the wrong way around. This is all you need to do to swap screens - & not lose me in the first 10 seconds of your talk... (Source: superuser.com/questions/11...)

Winding back the years at #ASM2025

This week’s highlights: 1. Paed ED said “my phone is full of photos of poo”. 2. Sent an ID Prof a Caddyshack DVD.

#POC25 Cheryl Johnson (Ngati Porou Oranga, NZ) on Indigenous Community-led Point of Care Testing: Cervical screening (pap smears) was not well adopted by Māori women who didn't like speculums. So self-collected swabs for HPV POCT is called "The Selfie" - brilliant! Increased screening is good.

#POC25: "Learn, unlearn and relearn" is Nikki Pant Pai's catch cry. We need to unlearn that molecular testing can only be done in laboratories.