www.biorxiv.org/content/10.6... Excited to share our new preprint: Not all microglia are the same. In this study, we identify a specialized ApoE-dependent program in the median eminence positioning microglial lipid metabolism as a driver of hypothalamic adaptation to nutritional stress.
Martin Valdearcos
@mvaldearcos.bsky.social
Valdearcos Lab at UCSF: Microglia, Neuroimmunology, Hypothalamus, Gut-Brain Axis, Metabolism.
I am grateful to have @skoliwad.bsky.social as my “science buddy”, someone with whom I feel comfortable and communicate effortlessly, someone who reliably brings up interesting angles on the things we are thinking about, and someone who can help us to overcome hurdles when we get stuck (Itai Yanai).
Q and A in Cell Reports @cp-cellreports.bsky.social with @skoliwad.bsky.social and @mvaldearcos.bsky.social on their recent paper www.cell.com/cell-reports...
Having a great time at the 2025 Obesity, Metabolism & Diabetes Research Retreat in partnership with UCSF Diabetes Center, UCSF Nutrition Obesity Research Center (NORC), @ucberkeleyofficial.bsky.social Metabolic Biology, and @ucdavis.bsky.social College of Biological Sciences
Proud of Emily McGrath, a PhD student in my lab, for being selected as a poster presenter winner in our DC/NORC retreat.
Excited to share our work on the role of hypothalamic microglia in the formation of glucoregulatory circuits. There is so much to learn about these fascinating cells. More to come from my own lab. Stay tuned!
New paper from @skoliwad.bsky.social and @mvaldearcos.bsky.social published in Cell Reports @cellpress.bsky.social www.cell.com/cell-reports...