Vander Heiden Lab at MIT

@mvhlab.bsky.social

The Vander Heiden Lab at the Koch Institute for Cancer Research at MIT studying how metabolism is altered to support inappropriate cancer cell proliferation. vanderheidenlab.mit.edu

Looking at human kidney cancer, we profiled nutrient levels in the tumor environment and found they are similar to nutrient levels in healthy kidney tissue, suggesting tumors must work within constraints of nutrients available rather than change nutrient environment. elifesciences.org/articles/95652

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

Assessing metabolites in renal cell carcinoma and kidney tissue suggests cancers adapt rather than dictate nutrient availability.

elifesciences.org